THE BIG 4 · DRUGS · DEVICES · DIAGNOSTICS · DIGITAL

Your region’s biotech news, every weekday morning.

National outlets cover the industry. Big4Bio covers your region: a curated daily briefing of the news, funding, deals, events, and hires that matter in each of the eight U.S. life science clusters, read every weekday morning since 2015.

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30,000+
SUBSCRIBERS
~40%
C-SUITE READERSHIP
8
REGIONAL BRIEFINGS
5
MORNINGS A WEEK
2015
PUBLISHING DAILY SINCE
CHOOSE YOUR REGION

Eight clusters. Eight daily briefings.

Every briefing is curated for its ecosystem: the companies, capital, institutions, and people of that region. Subscribe to your home hub, or to every market you serve.

WHAT READERS SAY

Required reading, by reputation.

“Out of all the industry newsletters, including Endpoints, I find Big4Bio to be the best.”
Shelley Amster
Co-Founder, 3Daughters
“First thing in the morning, I pour myself a cup of coffee and read Big4Bio.”
Clifford Brechner
Vice President, Colliers
"I read Big4Bio to quickly analyze the landscape - who's hiring, who's done a deal, and what data's been presented. Taken together, it gives you a real picture of a company's health and prospects — and you can see what people are talking about, what is driving our industry, in Boston versus San Francisco."
Greg Dombal
CEO, Franklin Life Science
THIS WEEK AT BIG4BIO

Beyond the morning briefing.

James Mackay, Ph.D.
CEO WEEKLY Q&A

James Mackay, Ph.D.

President & CEO, Crystalys Therapeutics. A new conversation with a life science CEO, every week.

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On Your Mark 2027
ON YOUR MARK 2027 · JANUARY 11–14 · SAN FRANCISCO

Make the most of JPM Week.

Big4Bio’s guide to the people, places, and opportunities surrounding the 45th Annual J.P. Morgan Healthcare Conference.

VISIT ON YOUR MARK →
Map of the eight U.S. life science regions covered in the Big4Bio book
THE BOOK

Mapping America’s Life Science Ecosystems

The definitive tour of the eight clusters we have covered daily for more than ten years. Hardcover, paperback, and eBook.

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FOR SPONSORS

Your brand, in the first email the industry reads.

Big4Bio sponsors reach a decade-built audience of decision-makers inside the exact regions they sell into, with placements from single regions to all-region programs, plus Company Spotlights, email blasts, and the Monthly Brief. Sponsors get the audience’s attention, not the editorial pen.

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SPONSOR PLACEMENTS · LOS ANGELES BRIEFING · APRIL 14, 2025 ISSUE
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VERIFIED SUBSCRIBERS
~40%
C-SUITE TITLES
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TARGETABLE REGIONS
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