Boston biotech companies are leading in new and improved research innovations and developments, diagnostics, treatments and more.
We’re pleased to provide our readers with this comprehensive directory of Greater Boston biotech companies. To learn more about these local businesses, simply search by company name or find alphabetically or by location or business. These listings are provided courtesy of BioPharmGuy, the premier resource for worldwide biotech company data.
To add your company, update information, or to highlight your company in the Big4Bio:Boston newsletter, please contact us at info@big4bio.com.
| Company Name | City | State | Business |
|---|---|---|---|
| 1910 Genetics | Boston | MA | Computational chemistry platform to develop small molecule therapeutics |
| 206 Ortho | Lowell | MA | Bioresorbable bone-growth material |
| 3-D Matrix | Needham | MA | Matrix for cellular / tissue growth |
| 3-D Matrix | Woburn | MA | Matrix for cellular / tissue growth |
| 3Derm Systems | Boston | MA | AI to automate Dermatological Care |
| 4Clinics | Cambridge | MA | Clinical Services |
| 4D Path | Newton | MA | Precision Oncology Platform |
| 4G Clinical | Wellesley | MA | Clinical Trial Software |
| 908 Devices | Boston | MA | Pre-Mass spec prep device |
| AB Biosciences | Concord | MA | Reagents, some protein research for therapeutic discovery |
| Abata Therapeutics | Cambridge | MA | Treg Cell Therapies |
| AbbVie | Worcester | MA | Biologics |
| Abcam | Cambridge | MA | Antibodies |
| ABclonal | Woburn | MA | Antibodies & Related Services |
| Abcuro | Newton | MA | T Cell Therapy, Antibodies |
| Aberjona Laboratories | Woburn | MA | Contract Medicinal Chemistry |
| Abiomed | Danvers | MA | Medical Devices |
| AblaCor | Needham | MA | Catheter Ablation System |
| Abpro | Woburn | MA | Antibodies |
| Abveris | Canton | MA | Custom Antibodies |
| Accent Therapeutics | Lexington | MA | RNA-modifying protein inhibitors |
| Access Vascular | Bedford | MA | Hydrogel-based devices to improve venous access |
| Acer Therapeutics | Newton | MA | Ultra-Orphan Drugs |
| Acpharis | Holliston | MA | Homology modeling of proteins, high throughput virtual screening of databases, and the assessment of compounds |
| Acrivon Therapeutics | Watertown | MA | Checkpoint Inhibitor |
| ACROBiosystems | Cambridge | MA | ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics, vaccines, and diagnostics. |
| Activ Surgical | Boston | MA | Surgical Software |
| ActivMed Practices and Research | Methuen | MA | Clinical Research |
| Acuity Spatial Genomics | Watertown | MA | Spatial 3D Genomics |
| Acworth Pharmaceuticals | Cambridge | MA | Cancer Therapies |
| Adagio Therapeutics | Waltham | MA | Antibodies |
| Adaptilens | Boston | MA | Intraocular Lenses |
| Adecto Pharmaceuticals | Boston | MA | Antibody-based Cancer Therapies |
| Adeptrix | Beverly | MA | Bead Assisted Mass Spec |
| Admetsys | Boston | MA | Artificial pancreas for hospital setting |
| Advanced Image Enhancement | Fall River | MA | Image enhancement algorithms for radiology |
| Advanced Instruments | Norwood | MA | Lab instruments |
| Advanced Proteome Therapeutics | Boston | MA | Improving Pharmacokinetics |
| Advirna | Worcester | MA | RNAi Technology Platform |
| Aerium Therapeutics | Boston | MA | Antibody, Small Molecules for Covid |
| Aerovate Therapeutics | Boston | MA | Inhaled Version of Imatinib |
| Affini-T Therapeutics | Watertown | MA | TCR Cell Therapy |
| Affinia Therapeutics | Waltham | MA | Gene Delivery |
| AffyImmune Therapeutics | Natick | MA | CAR-T Cell Therapy |
| AG Mednet | Boston | MA | Clinical Data Solutions |
| Agenus | Lexington | MA | Biologics |
| Agilent | Lexington | MA | High-Throughput Screening Equipment |
| Agios Pharmaceuticals | Cambridge | MA | Small Molecules |
| AGTC | Cambridge | MA | Gene Therapy |
| Aileron Therapeutics | Boston | MA | Perpetually Active Peptides |
| Aisa Pharma | Boston | MA | Raynaud's Treatment |
| Ajax Therapeutics | Cambridge | MA | Computational chemistry and structural biology |
| Akebia Therapeutics | Cambridge | MA | Small Molecules |
| Akouos | Boston | MA | Gene Therapy for Hearing Disorders |
| Akston Biosciences | Beverly | MA | Development and Manufacture of Fusion Protein Therapeutics |
| Aktis Oncology | Cambridge | MA | Targeted radiopharmaceuticals |
| Alacrita | Waltham | MA | Alacrita is a life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| Albireo Pharma | Boston | MA | Small Molecules? |
| Alcresta Therapeutics | Newton | MA | Digestive enzyme device |
| Alcyone Therapeutics | Lowell | MA | Gene Therapy |
| Aldatu Biosciences | Watertown | MA | HIV drug resistance phenotyping |
| Aldeyra Therapeutics | Lexington | MA | Aldehyde-trap therapies |
| Aleta Biotherapeutics | Natick | MA | Cell Therapy |
| Alexion Pharmaceuticals | Boston | MA | Biologics |
| ALine Biosciences | Woburn | MA | Genetic Sequencing & Purification |
| Alira Health | Boston | MA | Consulting |
| Alitair Pharmaceuticals | Hingham | MA | Specialty Pharmaceuticals |
| Alkermes | Waltham | MA | Small Molecules |
| Alkeus Pharmaceuticals | Somerville | MA | Ophthalmics |
| Allarity Therapeutics | Cambridge | MA | Cancer Treatments with Companion Diagnostics |
| AllCells | Quincy | MA | Cytokines, Stem Cells, Media, etc. |
| Allena Pharmaceuticals | Newton | MA | Non-Systemic, oral protein therapeutics |
| Allievex | Marblehead | MA | Novel Therapies for the Treatment of Rare Pediatric Neurodegenerative Diseases |
| Alloplex Biotherapeutics | Cambridge | MA | Cell Therapies |
| Allorion Therapeutics | Natick | MA | Small molecule drugs against cancer and autoimmune diseases |
| AlloVir | Cambridge | MA | Allogeneic, Off-The-Shelf, Multi-Virus Specific T-Cell Immunotherapies |
| Alloy Therapeutics | Lexington | MA | Antibody Discovery Platform |
| Allurion Technologies | Natick | MA | Gastric Balloon |
| Alnylam Pharmaceuticals | Cambridge | MA | RNAi |
| Alopexx Oncology | Concord | MA | Oncology drug |
| Alopexx Pharmaceuticals | Concord | MA | Monoclonal antibody |
| Alopexx Vaccine | Concord | MA | Vaccine |
| Alpaqua | Beverly | MA | Magnet Plates, Automation Accessories |
| Alphageneron Pharmaceuticals | Cambridge | MA | Natural Killer Therapy |
| Alzheon | Framingham | MA | Small Molecules targeting Alzheimer's |
| AMAG Pharmaceuticals | Waltham | MA | Small Molecules |
| Amathus Therapeutics | Medfield | MA | Small molecule modulators of organelle specific chaperones |
| Ambergen | Watertown | MA | Assay & Detection Technology |
| Amgen | Cambridge | MA | Small Molecules, Biologics |
| Amgen | Woburn | MA | Biologics |
| Amide Tech | Cambridge | MA | Peptide Synthesis |
| Amorphex Therapeutics | Andover | MA | Ocular Drug Delivery |
| Amorsa Therapeutics | Southborough | MA | Non-invasive therapeutic agents based on proprietary ketamine analogs |
| AMS Biotechnology | Cambridge | MA | Numerous assays, reagents and lab tools of all types |
| Amsel Medical | Cambridge | MA | Vessel Closure Device |
| Amylyx Pharmaceuticals | Cambridge | MA | Combination of existing products |
| Anagenesis Biotechnologies | Boston | MA | Cell therapy, small molecules |
| Analgesic Solutions | Wayland | MA | Clinical Trial Consulting |
| Analogic | Peabody | MA | Medical Imaging |
| Angiex | Cambridge | MA | Antibody-Based Therapeutics |
| Anika Therapeutics | Bedford | MA | Small Molecules |
| Anji Pharmaceuticals | Cambridge | MA | High-value targets validated by human genetics |
| Anodyne Nanotech | Boston | MA | Nanotech for Drug Delivery |
| Anoixis | Natick | MA | Pharmacometric Services |
| Anthos Therapeutics | Cambridge | MA | Antibody Therapeutics |
| AnTolRx | Cambridge | MA | Nanoparticle-based Therapies |
| Anumana | Cambridge | MA | AI ECG reading |
| Anuncia | Lowell | MA | Hydrocephalus Treatment |
| AOBiome | Cambridge | MA | Bacterial skin therapy |
| Apellis Pharmaceuticals | Waltham | MA | Cyclic peptide analog |
| Aphios | Woburn | MA | Small Molecules, 'Green' Biotechnology |
| Apic Bio | Cambridge | MA | Gene Therapy |
| Apnimed | Cambridge | MA | Sleep Apnea Drugs |
| Applied BioMath | Concord | MA | Systems Pharmacology & Mechanistic Modeling for Drug R&D |
| Applied Tissue Technologies | Hingham | MA | Wound Care |
| Apriori Bio | Cambridge | MA | |
| Aquilus Pharmaceuticals | Woburn | MA | Small Molecules |
| Aquinnah Pharmaceuticals | Cambridge | MA | ALS targeting drugs |
| Aramis Biosciences | Medfield | MA | Immuno-ophthalmology |
| Arbor Biotechnologies | Cambridge | MA | CRISPR enzymes |
| Arc Bio | Cambridge | MA | NGS for pathogen detection |
| Arch Therapeutics | Framingham | MA | Surgical device - hemostat, fluid leakage prevention |
| argenx | Boston | MA | Antibody therapies |
| Ariana Pharma | Cambridge | MA | Clinical & Biomarker Data Analytics |
| Arietis Pharma | Boston | MA | Small Molecule Antibiotics |
| Arkuda Therapeutics | Watertown | MA | Small Molecule for Dementia |
| Arrakis Therapeutics | Waltham | MA | RNA-targeted small molecules |
| Arranta Bio | Watertown | MA | CDMO |
| Arsenal Medical | Waltham | MA | Therapeutic foam technology |
| Artax Biopharma | Cambridge | MA | Small molecule |
| Arthrosurface | Franklin | MA | Joint Replacement Solutions |
| Artificial Axon Labs | Topsfield | MA | Drug discovery platform to find medicines for neurodegenerative diseases |
| Artugen Therapeutics | Concord | MA | Live Bacterial Treatments |
| Arxspan | Billerica | MA | ELN & Scientific Workflow Solutions |
| Ascidian Therapeutics | Boston | MA | Mutated exon replacement |
| Asimov | Boston | MA | Synthetic Biology |
| Associates of Cape Cod | East Falmouth | MA | Endotoxin Testing |
| AstraZeneca | Waltham | MA | Small Molecules, Biologics |
| Astria Therapeutics | Boston | MA | Monoclonal Antibody |
| Astrocyte Pharmaceuticals | Cambridge | MA | Treatment of TBI, Stroke, and Alzheimer’s Disease, and other injuries to the brain |
| Asymmetrex | Boston | MA | Adult stem cell 'production' |
| Atalanta Therapeutics | Boston | MA | RNAi therapeutics |
| Atavistik Bio | Cambridge | MA | High-throughput screening platform to identify allosteric modulators of proteins |
| Atea Pharmaceuticals | Boston | MA | Nucleoside and nucleotide analogs to inhibit the viral RNA polymerase |
| Aulos Bioscience | Cambridge | MA | IL-2 binding monoclonal antibodies |
| Aura Biosciences | Cambridge | MA | Delivery by Pseudo-Viruses |
| Auron Therapeutics | Wellesley | MA | Differentiation Therapy |
| Autocam Medical | Plymouth | MA | Precision-Machined Medical Devices, Implants |
| Avania | Marlborough | MA | Medical Device Clinical Research |
| Avastus Preclinical Services | Cambridge | MA | Preclinical Services |
| Avectas | Cambridge | MA | Non-Viral Cell Manufacturing Technology |
| Avenge Bio | Hingham | MA | Cell & Gene Therapies |
| AVEO Oncology | Boston | MA | Small Molecules |
| Averica Discovery | Marlborough | MA | Contract Research (Chemistry, Small Molecules) |
| Aveta Biomics | Bedford | MA | Small Molecule for Bone Disease |
| Aviceda Therapeutics | Cambridge | MA | Next generation of glyco-immune therapeutics |
| AVROBIO | Cambridge | MA | Cellular & Gene Therapies |
| Axcella Health | Cambridge | MA | Amino acid mediated therapeutics |
| Axial Therapeutics | Waltham | MA | Neurology-Microbiome research |
| Axoft | Cambridge | MA | Implantable Neuro Probes |
| Axonis Therapeutics | Cambridge | MA | |
| AZTherapies | Boston | MA | Combination small molecules |
| Azurity Pharmaceuticals | Woburn | MA | Compounding Kits |
| Azzur | Waltham | MA | Consulting |
| Bach Pharma | North Andover | MA | Treatments for oxidative stress related diseases |
| Batavia Biosciences | Woburn | MA | Early Stage Product Development Services |
| Be Biopharma | Cambridge | MA | Engineered B Cells |
| Beacon Clinical Research | Quincy | MA | Clinical Research |
| Beam Therapeutics | Cambridge | MA | CRISPR-based drug discovery |
| Beantown Biotech | Natick | MA | Contract Research services. Molecular Biology, Cell Biology, Biochemistry |
| Becton Dickinson | Billerica | MA | Lots of Biotechnology Products |
| Beeken Biomedical | Stoughton | MA | Hemostasis Products |
| BeiGene | Cambridge | MA | Small Molecules, Monoclonal Antibodies |
| BenuBiopharma | Natick | MA | Virtual Product Development Consulting |
| Bessor Pharma | Framingham | MA | Transferring Drugs from Academia to Industry |
| BGI | Cambridge | MA | Sequencing & Bioinformatics services |
| BIAL Biotech | Cambridge | MA | Small Molecules for neurodegenerative disorders |
| Bicara Therapeutics | Cambridge | MA | Dual-Action Biologics, Antibodies |
| Bicycle Therapeutics | Lexington | MA | Peptides |
| Binx Health | Cambridge | MA | Medical, Consumer Diagnostics |
| Bio-techne | Devens | MA | In-vitro diagnostics devices |
| Bioagilytix | Boston | MA | Bioanalytical services, immunoassays, cell-based assays |
| BioAnalytix | Cambridge | MA | Biologics development using advanced analytics |
| BioAxone Biosciences | Boston | MA | Regenerative Medicine |
| BioBridges | Wellesley | MA | Consulting |
| Biochempeg | Watertown | MA | PEG-derivatives |
| Biocytogen | Wakefield | MA | CRISPR genome editing, preclinical services |
| Biofourmis | Boston | MA | AI for adverse event prediction |
| Biogen | Cambridge | MA | Small Molecules, Biologics |
| Biolojic Design | Boston | MA | AI-based Multibody technology |
| Biomere | Worcester | MA | Contract Research, Development, Manufacturing |
| bioMerieux | Cambridge | MA | Diagnostics |
| Biomodels | Waltham | MA | Contract Preclinical Work |
| BIOMODEX | Quincy | MA | 3D replicas of medical devices |
| BIONIK Laboratories | Watertown | MA | Robotic Rehabilitation |
| BioNTech | Cambridge | MA | mRNA, Vaccines, Biologics |
| BioPAL | Worcester | MA | MRI contrast reagents |
| Biopharma PEG Scientific Inc | Watertown | MA | Manufacturing and supplying PEG derivatives and PEG raw material |
| Biosensics | Newton | MA | Wearable Sensors |
| BioSignal Group | Acton | MA | Functional Brain Monitoring |
| Biostage | Holliston | MA | Regenerative Medicine Research Products |
| BioTeam | Middleton | MA | Scientific IT consulting |
| Bioxytran | Newton | MA | Modified hemoglobin therapy |
| Bipharm | Boston | MA | Chromosomal instability targeting |
| BISC Global | Boston | MA | Bioinformatics, machine learning and artificial intelligence, statistics |
| Bitome | Boston | MA | NMR Spectroscopy |
| Blue Oak Pharmaceuticals | Waltham | MA | Drugs for Brain Disorders |
| Blue Therapeutics | Waltham | MA | Non-narcotic Pain Relief |
| bluebird bio | Cambridge | MA | Gene Therapy, Cellular Extraction & Reintroduction |
| Bluefin Biomedicine | Beverly | MA | Cancer Treatments |
| Bluejay Diagnostics | Acton | MA | POC Diagnostics |
| Blueprint Medicines | Cambridge | MA | Small Molecule Discovery |
| BOA Biomedical | Cambridge | MA | Rapid Universal Pathogen Diagnosis |
| Bone Biologics | Burlington | MA | Orthobiologic Products |
| Boston Clinical Trials | Boston | MA | Clinical Research |
| Boston Immune Technologies & Therapeutics | Boston | MA | Immune-based Cancer Therapies, Monoclonal Antibodies |
| Boston Institute of Biotechnology | Southborough | MA | Contract Research & Development |
| Boston Oncology | Cambridge | MA | Establishing local manufacturing in emerging markets |
| Boston Pharmaceuticals | Cambridge | MA | Acquisition of products |
| Boston Scientific | Marlborough | MA | Medical Devices |
| Boston Therapeutics | Lawrence | MA | Compounds based on complex carbohydrate chemistry |
| BostonGene | Waltham | MA | Biomedical Software |
| BrickBio | Woburn | MA | Protein Engineering, Antibody Conjugation, Services |
| Bristol Myers Squibb | Devens | MA | Small Molecules, Biologics |
| Brooks Life Sciences | Chelmsford | MA | Sample Management, Automation, Storage |
| Bruker | Billerica | MA | Scientific Instruments |
| Burke Bioventures | Cambridge | MA | Life Science Consulting |
| BVI Medical | Waltham | MA | Ophthalmic devices |
| BYOMass | Sudbury | MA | Metabolic Therapies |
| C4 Therapeutics | Watertown | MA | Ubiquitin-proteasome system based therapeutics |
| Caliber Imaging & Diagnostics | Andover | MA | Skin Imaging, Slide Imaging |
| Cambridge Isotope Laboratories | Tewksbury | MA | Stable Isotopes |
| Camena Bioscience | Newton | MA | Nucleic acid synthesis technology |
| CAMP4 Therapeutics | Cambridge | MA | 4D Gene Circuitry Platform |
| Candel Therapeutics | Needham | MA | Oncolytic Viral Immunotherapies for Cancer |
| Cantata Bio | Cambridge | MA | Multi-dimensional NGS technologies |
| Caraway Therapeutics | Cambridge | MA | Discovery of novel treatments for neurodegeneration, cognition and rare diseases |
| Carbon Biosciences | Lexington | MA | Gene Therapy |
| CardioFocus | Marlborough | MA | Pulmonary vein ablation device |
| Cardurion Pharmaceuticals | Boston | MA | Cardiovascular treatments |
| Carna Biosciences | Natick | MA | Drug discovery products & services |
| Casma Therapeutics | Cambridge | MA | Autophagy-focused Treatments |
| Catalog | Boston | MA | DNA data storage |
| Catamaran Bio | Cambridge | MA | CAR-Natural Killer Cell Therapies |
| CATO SMS | Waltham | MA | Full Service Contract Research |
| Cedilla Therapeutics | Cambridge | MA | Small Molecules for Undruggable Protein Targets |
| Cell Essentials | Boston | MA | Antibody Production & Cell Biology-Based Services |
| Cell Sciences | Newburyport | MA | Proteins, Reagents, Kits |
| Cell Sciences | Newburyport | MA | Lab Reagents, Antibodies |
| Cell Signaling Technology | Danvers | MA | Antibodies, ELISA kits, research products |
| Cellanyx Diagnostics | Beverly | MA | Cancer diagnostic |
| Cellaria Biosciences | Wakefield | MA | In-vitro disease models |
| Cellarity | Cambridge | MA | Drug Discovery, Unknown Modalities |
| Cellay | Cambridge | MA | Same Day FISH Probes |
| Celldex Therapeutics | Fall River | MA | Small Molecules, Biologics, Vaccines |
| Celldex Therapeutics | Needham | MA | Small Molecules, Biologics, Vaccines |
| Cellero | Lowell | MA | Cell Products |
| Cellink | Boston | MA | Bioprinting |
| Cellino Biotech | Cambridge | MA | Cell therapies |
| Celsius Therapeutics | Cambridge | MA | RNA sequencing for drug discovery, Antibody-drug conjugates |
| Centaur Labs | Boston | MA | Medical data labeling including classification and segmentation for X-ray, CT, MRI, ultrasound, image, video, text etc. |
| Centessa Pharmaceuticals | Boston | MA | Umbrella company acquiring drug companies |
| Centrexion Therapeutics | Boston | MA | Pain therapies |
| CeQur | Marlborough | MA | Insulin pump |
| Cerevance | Boston | MA | CNS small molecules |
| CereVasc | Auburndale | MA | Minimally-Invasive Hydrocephalus Treatment |
| Cerevel Therapeutics | Boston | MA | Neuro |
| Charles River Laboratories | Wilmington | MA | Research Animal Models and Preclinical Research |
| Charles River Laboratories | Shrewsbury | MA | Research Animal Models and Preclinical Research |
| Checkmate Pharmaceuticals | Cambridge | MA | Cancer Immunotherapy |
| ChemGenes | Wilmington | MA | DNA / RNA synthesis |
| Chromettex | Milford | MA | Chromettex Analytical Services is a provider of chromatography instrumentation services |
| CinCor Pharma | Waltham | MA | Treatment for hypertension and other cardio-renal diseases |
| Cisbio | Bedford | MA | Assays |
| Civetta Therapeutics | Cambridge | MA | Small molecule targeting of beta-propeller domains |
| Claritas Therapeutics | Beverly | MA | Nitric-oxide Releasing Therapies |
| Clear Creek Bio | Cambridge | MA | Small Molecule |
| ClearB Therapeutics | Concord | MA | Hepatitis B Vaccine |
| Clozex Medical | Wellesley | MA | Surgical Skin Closures |
| Cocoon Biotech | Cambridge | MA | Biocompatible silk protein |
| Codiak BioSciences | Cambridge | MA | Exosomes |
| Cogent Biosciences | Cambridge | MA | Cellular immunotherapies |
| Cogmedix | West Boylston | MA | Medical Device Contract Manufacturing |
| Cognito Therapeutics | Cambridge | MA | Device-based Brain Therapies |
| Cognoptix | Concord | MA | Eye scanning diagnostic |
| Collagen Medical | Belmont | MA | MRI contrast agents |
| Collegium Pharmaceutical | Stoughton | MA | Drug Release Technology |
| ColonaryConcepts | Newton | MA | Colon Prep Foods |
| Compass Biomedical | Hopkinton | MA | Cell Culture Products, Platelet Separator |
| Compass Therapeutics | Boston | MA | Antibody Therapies |
| Concert Pharmaceuticals | Lexington | MA | Small Molecule Discovery |
| ConcertAI | Boston | MA | Oncology Contract Research |
| Confer Health | Boston | MA | At-home Diagnostics |
| ConforMIS | Billerica | MA | Knee replacement implants, customized orthopedics |
| CONMED | Westborough | MA | Surgical, Medical Devices |
| Constant Therapeutics | Boston | MA | Peptide Treatments |
| CONTINUUS Pharmaceuticals | Woburn | MA | Continuous small molecule manufacturing |
| Corbus Pharmaceuticals | Norwood | MA | Orphan inflammatory-fibrotic diseases |
| Corindus Vascular Robotics | Waltham | MA | Robotic surgery devices |
| CorticoMetrics | Boston | MA | Post-acquisition quantitative analysis of MRI brain scans |
| Cortria | Waltham | MA | Small Molecules |
| Corvia Medical | Tewksbury | MA | Interatrial Shunt |
| CovalX | Saugus | MA | Protein Complex Analysis |
| Covaris | Woburn | MA | DNA Sample Prep |
| CreaGen | Woburn | MA | Drug Discovery Services |
| CRISPR Therapeutics | Cambridge | MA | CRISPR-Cas9 therapy |
| CROMSOURCE | Waltham | MA | Clinical Research, Consulting |
| Crown Bioscience | Cambridge | MA | Drug Development |
| Crozet BioPharma | Devens | MA | Contract Research |
| CSA Medical | Lexington | MA | Spray Cryotherapy |
| Cue BioPharma | Cambridge | MA | Immunotherapy |
| Cugene | Waltham | MA | Cancer and Inflammation Treatments |
| Cullinan Oncology | Cambridge | MA | In-Licensing & Developing Oncology Assets for Sale |
| CureLab Oncology | Boston | MA | Anti-Cancer Biologics |
| Curelator | Cambridge | MA | Digital platform for tracking migraine symptoms |
| Cureport | Worcester | MA | Nanomedicines |
| CureVac | Boston | MA | MRNA treatments |
| Curia | Burlington | MA | Contract Research |
| Curiox Biosystems | Woburn | MA | Assay Platform |
| CuriRx | Wilmington | MA | CuriRx is a leading CRO, offering development services for upstream and downstream bioprocess, formulation, lyophilization, analytical development, analytical testing services including the CuriLytics™ platform with high-resolution CMC analytical services. |
| Curis | Lexington | MA | Small Molecules |
| CXL Ophthalmics | Sherborn | MA | Minimally-invasive treatment for keratoconus |
| Cyclerion Therapeutics | Cambridge | MA | Small Molecules |
| Cygnal Therapeutics | Cambridge | MA | Exoneural Treatments |
| Cynosure | Westford | MA | Hair removal device |
| Cyprotex | Watertown | MA | Contract research organization offering full range of ADME-Tox services (part of the Evotec Group) |
| Cystosure | Holliston | MA | Urinary Catheter |
| Cyta Therapeutics | Lowell | MA | Liver Regeneration Therapies |
| Cyteir Therapeutics | Lexington | MA | Rapid destruction of cancer cells |
| Cytel | Cambridge | MA | Clinical software, statistical services |
| Cytel | Waltham | MA | Clinical software, statistical services |
| CYTOO | Cambridge | MA | High Content Screening |
| Cytovia Therapeutics | Cambridge | MA | Gene-Edited iPSC-Derived Natural Killer Cells |
| Cytrellis Biosystems | Woburn | MA | Medical devices for aesthetics |
| Day Zero Diagnostics | Boston | MA | Machine learning to determine antibiotic resistance from genomic data |
| Decibel Therapeutics | Boston | MA | New medicines to protect, restore & repair hearing |
| Deciphera Pharmaceuticals | Waltham | MA | Small Molecules |
| DeepBiome Therapeutics | Allston | MA | Microbiome Drug Discovery |
| DeepCure | Boston | MA | AI Drug Discovery |
| Delix Therapeutics | Boston | MA | Psychoplastogens |
| DePuy Synthes | Raynham | MA | Medical Devices |
| DermBiont | Boston | MA | Topical Bacterial Products |
| Design Pharmaceuticals | Cambridge | MA | Small Molecule Drug & Design |
| DeuteRx | Andover | MA | Chiral switching of existing therapies / candidates |
| Dewpoint Therapeutics | Boston | MA | Biomolecular Condensates |
| Diagnosys | Lowell | MA | Visual electrophysiology systems |
| Dicerna Pharmaceuticals | Cambridge | MA | RNAi |
| Differentiated Therapeutics | Boston | MA | Targeted Protein Degradation |
| Digilab | Hopkinton | MA | Genomics, Proteomics |
| Directed Genomics | Watertown | MA | Specializing in the development and optimization of Next Generation Sequencing solutions |
| Disc Medicine | Cambridge | MA | Drugs to regulate hepcidin expression within the body |
| Dompé | Boston | MA | Biologics, Small Molecules, OTC |
| DoubleRainbow Biosciences | Cambridge | MA | Drug discovery through genetic analysis of nature |
| Dragonfly Therapeutics | Waltham | MA | Immuno-oncology Drugs |
| DropGenie | Boston | MA | Automated Gene Editing |
| DynamiCure | Cambridge | MA | IO Immunotherapy |
| Dyne Therapeutics | Waltham | MA | Antibody-Oligonucleotide Treatments for Muscle Diseases |
| Dyno Therapeutics | Cambridge | MA | AAV Engineering |
| Dynocardia | Lowell | MA | Cuff-less Blood Pressure Monitor |
| EBT Medical | Hopkinton | MA | Neuromodulation Pelvic Floor Treatments |
| Editas Medicine | Cambridge | MA | Genome Editing Therapies (CRISPR) |
| eGenesis | Cambridge | MA | CRISPR for xenotransplantation |
| Eikonizo Therapeutics | Cambridge | MA | Brain-penetrant Small Molecules |
| EIP Pharma | Boston | MA | Alzheimer's treatment |
| Eisai | Cambridge | MA | Small Molecules |
| Elektrofi | Boston | MA | Biologics Formulation |
| Element | Acton | MA | Element: Antimicrobial, Pharma, Biotech, Med Device & Healthcare testing solutions. Element is FDA registered, DEA licensed, ISO/IEC 17025:2017 accredited |
| Elevian | Allston | MA | Blood components to fight aging |
| Eli Lilly | Cambridge | MA | Small Molecules, Biologics |
| Elicio Therapeutics | Cambridge | MA | HPV-induced cancer treatments |
| Elpis Biopharmaceuticals | Lexington | MA | Cellular & Biologic Therapies |
| Elucid Bio | Boston | MA | Arterial Analysis Software |
| Embera NeuroTherapeutics | Sudbury | MA | Addiction Therapies |
| EMD Serono | Billerica | MA | Small Molecules, Biologics |
| EMD Serono | Rockland | MA | Biologics |
| Empatica | Boston | MA | Seizure Detection |
| Empiriko | Newtown | MA | Drug metabolite creation for drug discovery |
| Empress Therapeutics | Cambridge | MA | Co-Evolved Medicines |
| Emulate | Boston | MA | Organs-on-chips |
| Enanta Pharmaceuticals | Watertown | MA | Small Molecules |
| EnClear Therapies | Newburyport | MA | ALS Treatment Device |
| EndoCellutions | Marshfield | MA | Regenerative Medicine |
| Energesis Pharmaceuticals | Cambridge | MA | Therapies targeting brown adipose fat tissue |
| EnPlusOne Biosciences | Watertown | MA | Enzymatic RNA Synthesis Platform |
| Enrich Therapeutics | Worcester | MA | Single Cell Isolation |
| ENSEM Therapeutics | Medford | MA | Characterizing rare conformational states in drug targets |
| Ensoma | Boston | MA | in vivo Gene Therapy |
| Entasis Therapeutics | Waltham | MA | Small molecule anti-infectives |
| Enterome | Cambridge | MA | Microbiome-related diseases, diagnostics |
| Entrada Therapeutics | Boston | MA | Biologics delivered to cytosol |
| entrinsic bioscience | Norwood | MA | Amino Acid Treatments |
| EpigenDx | Hopkinton | MA | Genomic & Epigenomic Services |
| EQRx | Cambridge | MA | Creating novel, cheap drugs |
| Era7 Bioinformatics | Cambridge | MA | Next-gen sequencing analytics |
| Erbi Biosystems | Woburn | MA | Miniaturized Bioreactors |
| Ergomed | Waltham | MA | Clinical Research |
| Ergosuture | Boston | MA | Surgical Devices |
| Erytech Pharma | Cambridge | MA | Loading Red-Blood Cells with Therapeutics |
| Eton Bioscience | Charlestown | MA | Research Reagents, Kits, Peptides, Services, etc. |
| Eumentis Therapeutics | Boston | MA | Novel therapeutics for the treatment of neuropsychiatric diseases |
| Eurofins Lancaster Laboratories | Waltham | MA | Contract Laboratory |
| Eutropics Pharmaceuticals | Cambridge | MA | Cancer Diagnostics |
| Evelo Biosciences | Cambridge | MA | Microbiomic cancer treatments |
| Exacis Biotherapeutics | Cambridge | MA | mRNA-based technology to develop engineered cell therapies for solid and liquid tumors |
| Exalpha Biologicals | Shirley | MA | Antibodies, Assay Kits, Enzymes |
| Exegenesis Bio | Boston | MA | Gene Therapy |
| Exergen | Watertown | MA | Noninvasive Thermometers |
| eXIthera Pharmaceuticals | Westborough | MA | Small molecule inhibitors of Factor XIa |
| Exo Therapeutics | Cambridge | MA | Small Molecule Drug Discovery |
| Exogenesis | Billerica | MA | Nano-technology Medical Devices |
| Exosome Diagnostics | Waltham | MA | Biofluid-based molecular diagnostic tests |
| Expansion Technologies | Cambridge | MA | Diagnostics |
| Extend Biosciences | Newton | MA | Sustained delivery of peptides |
| Eyegate Pharma | Waltham | MA | Drug Delivery, Ocular Drugs |
| EyePoint Pharmaceuticals | Watertown | MA | Miniaturized, sustained-release drug delivery products |
| F-star Therapeutics | Cambridge | MA | Antibody Engineering |
| Factor Bioscience | Cambridge | MA | RNA Reprogramming Technology |
| Faze Medicines | Cambridge | MA | Treatments for Disease-Causing Condensates |
| Felicitex Therapeutics | Natick | MA | Cancer drug discovery |
| FerGene | Cambridge | MA | Treatment for non-muscle invasive bladder cancer |
| Finch Therapeutics | Somerville | MA | Microbiological Therapy |
| First Light Diagnostics | Chelmsford | MA | Benchtop Sample Analysis |
| Fitzgerald Industries International | Acton | MA | Primary and Secondary Antibodies, Recombinant Proteins & ELISA Kits |
| Flare Therapeutics | Cambridge | MA | Therapeutics Targeting Transcription Factors |
| Fluent BioSciences | Watertown | MA | Single Cell Analysis Without Complex Instrumentation |
| Fog Pharmaceuticals | Cambridge | MA | Cell-penetrating miniproteins |
| Foghorn Therapeutics | Cambridge | MA | Cancer Drug Discovery |
| Follica | Boston | MA | Hair follicle regrowth device/drug regimen |
| Formulatrix | Bedford | MA | Lab Automation |
| Fortress Biotech | Waltham | MA | Small Molecules, Helminth worm eggs as a drug |
| Foundation Medicine | Cambridge | MA | Diagnostic Assay |
| Fractyl Health | Lexington | MA | Thermal ablation therapy |
| Frameshift Labs | Boston | MA | Genomic Data Visualization |
| Frenova Renal Research | Waltham | MA | Renal clinical research |
| Frequency Therapeutics | Woburn | MA | Small molecules that activate progenitor cells |
| Fulcrum Therapeutics | Cambridge | MA | Unlocking gene control mechanisms to develop small molecule therapies |
| G3 Pharmaceuticals | Lexington | MA | Galectin-3 Targeting |
| Galatea Surgical | Lexington | MA | Surgical Scaffolds |
| Garuda Therapeutics | Natick | MA | Off-the-shelf hematopoietic stem cell therapies |
| Gatehouse Bio | Waltham | MA | RNA sequencing for Drug Targets & Biomarkers |
| Gel4Med | Allston | MA | Programmable Material for Tissue Regeneration |
| Gelesis | Boston | MA | Small Molecules? |
| GelMedix | Newton | MA | Biomaterials for improved drug delivery |
| Gemini Therapeutics | Cambridge | MA | Genetically-targeted Ophthalmology Medicine |
| Geneius Biotechnology | Natick | MA | Autologous, adoptive T-cell therapies |
| Gener8 | Woburn | MA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Generate Biomedicines | Cambridge | MA | Machine Learning for Therapeutic Protein Design |
| Generation Bio | Cambridge | MA | Gene Therapy |
| Genfit | Cambridge | MA | Drug Discovery |
| Genosco | Billerica | MA | Small Molecules |
| Genoskin | Salem | MA | ex vivo Clinical Testing |
| GenoSpace | Boston | MA | Platform for genomic data |
| Genovis | Cambridge | MA | Nanoparticles |
| Genuity Science | Boston | MA | Genomic Data Platform |
| Genus Oncology | Boston | MA | Peptide Therapy Targeting MUC1 |
| GI Dynamics | Boston | MA | Device to prevent digestion and promote weight loss |
| Ginkgo Bioworks | Boston | MA | Engineered Organisms |
| GL Synthesis | Worcester | MA | Chemical Synthesis & Production |
| GLG Pharma | Salem | MA | Precision Oncology |
| GliaCure | Boston | MA | Neurological and neuropsychiatric therapies |
| Glympse Bio | Cambridge | MA | Activity Sensors |
| Glytec | Waltham | MA | Predictive dosing algorithm for diabetes |
| GNS Healthcare | Cambridge | MA | Analytics |
| GO Therapeutics | Natick | MA | Antibody Therapeutics |
| Goldfinch Bio | Cambridge | MA | Kidney drugs |
| GoodCell | Waltham | MA | Personal Biobanking, Health Screenings |
| Granata Bio | Duxbury | MA | Fertility Treatments |
| GreenLight Biosciences | Medford | MA | Renewable Chemicals |
| Gritstone Bio | Cambridge | MA | Personalized cancer vaccines |
| GRO Biosciences | Boston | MA | Genetically altered bacteria for drug improvement |
| Guardian Therapeutics | Lexington | MA | Aptamer Therapeutics |
| GV20 Oncotherapy | Cambridge | MA | Antibody for Cancer |
| Haemonetics | Boston | MA | Blood Management Solutions |
| Hai Laboratories | Lexington | MA | Ophthalmic Equipment |
| Halloran Consulting Group | Boston | MA | Consulting |
| Harbour BioMed | Cambridge | MA | Antibodies and fragments |
| Harvard Bioscience | Holliston | MA | Scientific Instruments |
| hC Bioscience | Cambridge | MA | tRNA-based Therapeutics |
| HebeCell | Natick | MA | Cell Therapies |
| Helix Nanotechnologies | Cambridge | MA | DNA Therapy |
| HelixBind | Boxbourough | MA | Blood infection Diagnostics |
| Hemanext | Lexington | MA | Transfusion Technologies |
| Hemanext | Avon | MA | Transfusion Technologies |
| Hemedex | Waltham | MA | Perfusion monitoring |
| Hemera Biosciences | Waltham | MA | Gene Therapy |
| HepatoChem | Newburyport | MA | Drug Discovery Services |
| HighPassBio | Cambridge | MA | T cell immunotherapies |
| HighRes Biosolutions | Beverly | MA | Lab Automation Instruments |
| HilleVax | Boston | MA | Norovirus Vaccine |
| HipXpert | Medford | MA | Personalized Planning for Hip Replacement |
| Holobiome | Cambridge | MA | Microbiome Therapeutics Targeting Nervous System |
| Hologic | Marlborough | MA | Diagnostic, Imaging |
| Hologic | Methuen | MA | Diagnostic, Imaging |
| Homology Medicines | Bedford | MA | Gene-editing via homologous recombination |
| Hooke Laboratories | Lawrence | MA | Tissues and Related Lab Products |
| HotSpot Therapeutics | Boston | MA | Small Molecules designed for Distinct Protein Domains |
| HTI Medical | North Attleboro | MA | Diagnostics |
| Human Metabolome Technologies America | Boston | MA | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Hunterian Medicine | Cambridge | MA | CRISPR-based drug discovery |
| Hyalex Orthopaedics | Lexington | MA | Synthetic Cartilage |
| HydroCision | North Billerica | MA | Saline Jet Device |
| i2O Therapeutics | Allston | MA | Oral Biologics |
| ICQ Consultants | Southborough | MA | Commissioning, qualification, and validation services |
| IDRx | Plymouth | MA | Purpose-built precision combination therapies |
| IFM Therapeutics (2) | Boston | MA | Innate Immunity Therapeutics |
| Ikena Oncology | Boston | MA | Immuno-Oncology |
| ImaBiotech | Billerica | MA | Contract Mass Spec |
| Imagin Medical | Auburndale | MA | Surgical Imaging |
| Imara | Boston | MA | Sickle cell therapies |
| Imbria Pharmaceuticals | Boston | MA | Partial fatty acid oxidation (pFOX) inhibitor |
| Immuneering | Cambridge | MA | Bioinformatics for genomics |
| ImmuneID | Boston | MA | Antibody Discovery Platform |
| Immunitas Therapeutics | Waltham | MA | Single cell genomics-based drug discovery |
| ImmunoGen (2) | Waltham | MA | Biologics |
| immunoScape | Cambridge | MA | Immunotherapy Profiling Services |
| Infinity Pharmaceuticals | Cambridge | MA | Small Molecules |
| Inflammasome Therapeutics | Newton | MA | Therapies for prevalent, degenerative diseases as well as sustained-release drug delivery systems |
| InfoBionic | Waltham | MA | Arrhythmia detection and monitoring |
| InfraReDx | Bedford | MA | Medical Devices |
| Inhibikase Therapeutics | Boston | MA | Therapeutic Vaccines |
| Innovation Pharmaceuticals | Beverly | MA | Small Molecules |
| Inozyme Pharma | Boston | MA | Enzyme Replacement Therapy |
| Instylla | Waltham | MA | Hydrogel Technology for Radiological Purposes |
| Instylla | Bedford | MA | Embolization treatment |
| Insulet | Acton | MA | Insulin Pump |
| Intarcia Therapeutics | Boston | MA | Small Molecules |
| Integer | Raynham | MA | Medical & Surgical Devices |
| Integra LifeSciences | Billerica | MA | Medical Devices |
| Integra LifeSciences | Boston | MA | Medical Devices |
| Integral BioSystems | Bedford | MA | Drug Delivery Services |
| Intellia Therapeutics | Cambridge | MA | Therapeutic gene editing (CRISPR) |
| Intera Oncology | Wellesley | MA | Oncology and Neuromodulation Drug Delivery |
| Intergalactic Therapeutics | Boston | MA | Non-viral Gene Therapy |
| Interscope | Whitinsville | MA | Endoscopic Solutions |
| Intrinsic Imaging | Bolton | MA | Imaging for Clinical trials |
| Intrinsic Therapeutics | Woburn | MA | Lumbar Discectomy Implant |
| Invicro | Boston | MA | Imaging services & software |
| Invisio Medical | Winchester | MA | Portable Brain Imaging |
| Invitrometrix | Lowell | MA | Real-time in-vitro analysis |
| InVivo Therapeutics | Cambridge | MA | Neural-spinal scaffold |
| Inzen Therapeutics | Cambridge | MA | Novel class of medicines based on manipulating cellular turnover |
| Ipsen | Cambridge | MA | Small Molecules, Biologics |
| IQVIA | Cambridge | MA | Clinical Research |
| Ironwood Pharmaceuticals | Boston | MA | Small Molecules |
| Ischemix | Grafton | MA | Small Molecules |
| iSpecimen | Lexington | MA | Biospecimen Procurement |
| ISTO Biologics | Hopkinton | MA | Orthobiologics |
| iTeos Therapeutics | Cambridge | MA | Cancer Immunotherapy |
| Iterative Scopes | Cambridge | MA | Products & Services for Gastroenterology |
| Ivenix | North Andover | MA | Infusion pumps |
| iVexSol | Worcester | MA | Lentiviral vectors |
| Jana Care | Boston | MA | Smartphone connected diagnostic device |
| Janus Biotherapeutics | Wellesley | MA | Autoimmunity therapeutics |
| Javelin Biotech | Woburn | MA | Drug Analysis Technology |
| Jnana Therapeutics | Boston | MA | SLC transporter Drug Discovery |
| Jordi labs | Mansfield | MA | Analytical chemistry testing services |
| Jounce Therapeutics | Cambridge | MA | Cancer Immunotherapies |
| JPT Peptide Technologies | Acton | MA | Peptide products and services |
| JURA Bio | Somerville | MA | CAR-T Therapies |
| Kala Pharmaceuticals | Watertown | MA | Drug Delivery |
| KalVista Pharmaceuticals | Cambridge | MA | Ophthalmology Products |
| Karuna Therapeutics | Boston | MA | Schizophrenia treatment |
| Karyopharm Therapeutics | Newton | MA | Small Molecules |
| KBioBox | Worcester | MA | Genomic Analysis |
| Kephera Diagnostics | Framingham | MA | Point-of-Care Diagnostics |
| Kerafast | Boston | MA | Reagents for the Greater Good |
| Kern Systems | Brookline | MA | Synthetic DNA Data Storage |
| Kernal Biologics | Cambridge | MA | mRNA Therapies |
| Keros Therapeutics | Lexington | MA | Rare Muscle Disorders |
| KEW Group | Auburndale | MA | Cancer genetic information |
| Kinaset Therapeutics | Boston | MA | Novel, inhaled small-molecule pan-JAK inhibitor |
| KinDex Pharmaceuticals | Boston | MA | Repurposed small molecules |
| Kiniksa Pharmaceuticals | Lexington | MA | Biologics |
| Kira Pharmaceuticals | Cambridge | MA | Complement drug discovery |
| Kojin Therapeutics | Cambridge | MA | Small molecules targeting ferroptosis |
| Korro Bio | Cambridge | MA | RNA-editing Drugs |
| Kronos Bio | Cambridge | MA | First-in-class therapies against historically intractable targets |
| KSQ Therapeutics | Cambridge | MA | CRISPR-based drug discovery |
| Kumuda | Boston | MA | In Silico Drug Discovery |
| Kymera Therapeutics | Watertown | MA | Small Molecules acting to degrade proteins |
| Kytopen | Cambridge | MA | Gene-modified Cell Therapies |
| L.E.A.F. Pharmaceuticals | Woburn | MA | Re-Engineering Existing Molecules |
| LabMinds | Somerville | MA | Automated Solution Prep |
| LabTech | Hopkinton | MA | Sample Prep, lab equipment |
| LakePharma | Hopkinton | MA | Protein Engineering CRO |
| LakePharma | Worcester | MA | Protein Engineering CRO |
| Laminar Pharmaceuticals | Arlington | MA | Membrane Lipid Therapy, Synthetic Fatty Acids |
| Lantheus Medical Imaging | North Billerica | MA | Small Molecules for Imaging |
| Laronde | Cambridge | MA | Plasmid RNA Therapeutics |
| Latham Biopharm Group | Cambridge | MA | Consulting |
| LaunchWorks CDMO | Beverly | MA | Contract Manufacturing |
| Laurus Synthesis | Woburn | MA | Contract Development & Manufacturing |
| Leal Therapeutics | Worcester | MA | CNS Therapies |
| Lean Biologix | Norfolk | MA | Consulting |
| Leap Therapeutics | Cambridge | MA | Monoclonal antibody |
| LeMaitre Vascular | Burlington | MA | Vascular surgical devices |
| Lennham Pharmaceuticals | Concord | MA | Improving the metabolic and pharmacological profile of drugs through deuterium chemistry |
| Leukemia Therapeutics | Boston | MA | Antibody based drugs targeting leukemia |
| Leukocare Biotechnology | Milford | MA | Biologic Formulation |
| LifeMine Therapeutics | Cambridge | MA | Fungi-derived therapeutics |
| Lightpoint Medical | Cambridge | MA | Surgical Imaging Technology |
| LikeMinds | Boston | MA | Dopamine transporter imaging-agent platform |
| LogicBio Therapeutics | Lexington | MA | Gene Therapy |
| LUCA Biologics | Cambridge | MA | Treatment Targeting Vaginal Microbiome |
| Luciole Pharmaceuticals | Natick | MA | Small Molecules for mitochondrial DNA repair |
| Lucy Therapeutics | Cambridge | MA | Small molecule treatments for neurological diseases along with a unique peripheral mitochondrial biomarker |
| Lumicell | Newton | MA | Cancer imaging device technology |
| LUMICKS | Waltham | MA | Dynamic Single-Molecule analysis products |
| LumiraDx | Waltham | MA | Diagnostic Platform |
| Lutronic Vision | Billerica | MA | Macular Laser |
| Lykan Bioscience | Hopkinton | MA | Contract Manufacturing - Cell-based Therapies |
| Lyndra Therapeutics | Watertown | MA | Drug Delivery |
| LYNE LABS | Brockton | MA | Manufacturing Services |
| Lyra Therapeutics | Watertown | MA | Biomedical scaffold technology |
| Lytica Therapeutics | Cambridge | MA | Antimicrobial peptide Design |
| Magellan Diagnostics | North Billerica | MA | Biotech Products |
| Magenta Therapeutics | Cambridge | MA | Stem Cell, Bone Marrow Transplant Technology |
| MAK Scientific LLC | Burlington | MA | Drugs Targeting Endocannabinoid System |
| MANA Therapeutics | Waltham | MA | Off-the-shelf allogeneic cell therapies |
| Manifold Bio | Allston | MA | Measurement-driven drug design |
| MapLight Therapeutics | Boston | MA | Optogenetics |
| Marengo Therapeutics | Cambridge | MA | Monoclonal Antibodies |
| MarvelBiome | Woburn | MA | Microbial Therapeutics |
| Masy BioServices | Pepperell | MA | Validation, Calibration, Equipment Rentals, Storage, Monitoring Systems |
| Matchpoint Therapeutics | Cambridge | MA | Covalent Medicines |
| Matrivax Research and Development | Boston | MA | Encapsulation of Bacterial Pathogens |
| MatTek | Ashland | MA | Cell Products, Services |
| MayTrex Therapeutics | Milford | MA | Therapies Targeting Extracellular Matrix |
| MBL International | Woburn | MA | Antibodies, Research products, diagnostic products |
| MDC Associates | Beverly | MA | Regulatory Affairs, Quality Systems, CRO Services, and Commercial Support |
| MDX Lifesciences | Newton | MA | Autologous transplantation monitoring technology |
| Meadowhawk Biolabs | Marlborough | MA | Small & Large Molecule CRO |
| MedChem Partners | Lexington | MA | Contract Research |
| Median Technologies | Burlington | MA | Imaging Phenomics |
| Mediar Therapeutics | Cambridge | MA | |
| Medica Corp | Bedford | MA | In-vitro diagnostic analyzers |
| Medicept | Ashland | MA | Medical Device Compliance Consulting |
| MedSource | Cambridge | MA | Clinical Research |
| Medtronic | Danvers | MA | Medical Devices |
| Medtronic | Mansfield | MA | Medical Devices |
| Mellitus | Boston | MA | Diagnostic for gestational diabetes |
| Mercy BioAnalytics | Natick | MA | Early Cancer Diagnosis |
| Mersana Therapeutics | Cambridge | MA | Drug Delivery |
| Mevion Medical Systems | Littleton | MA | Radiation Therapy |
| Miach Orthopaedics | Boston | MA | Knee Orthopedics |
| Micro Medical Solutions | Wilmington | MA | Treatment for Critical Limb Ischemia |
| Micro-Leads | Somerville | MA | High-resolution spinal cord stimulation therapy for treating chronic focal pains of the low-back, trunk, extremities, and feet |
| Microbiotix | Worcester | MA | Small Molecules |
| Microbot Medical | Hingham | MA | Micro-robot assisted medical technologies |
| Microfluidics | Westwood | MA | High shear fluid processors |
| Microline Surgical | Belverly | MA | Minimally invasive therapeutic solutions |
| Microtissues | Sharon | MA | 3D Cell Culture |
| Millipore | Burlington | MA | Purification, Analytic Biologics, Discovery |
| Millipore | Bedford | MA | Purification, Analytic Biologics, Discovery |
| Millipore | Danvers | MA | Purification, Analytic Biologics, Discovery |
| Milu Labs | Cambridge | MA | Womens Diagnostics |
| MindChild Medical | North Andover | MA | Fetal Monitoring System |
| Minerva Biotechnologies | Waltham | MA | Cancer therapeutics, Stem Cells |
| Minerva Neurosciences | Waltham | MA | CNS treatments |
| miniPCR | Cambridge | MA | Miniature PCR machine |
| MiNK Therapeutics | Lexington | MA | Cell Therapy, CAR-T |
| Mispro Biotech Services | Cambridge | MA | Contract Vivarium Organization |
| Mitobridge | Cambridge | MA | Therapeutics to improve mitochondrial function |
| Modalis Therapeutics | Cambridge | MA | Genome Editing Tools |
| Moderna Therapeutics | Cambridge | MA | RNA Therapies |
| Moderna Therapeutics | Norwood | MA | RNA Therapies |
| ModeX Therapeutics | Natick | MA | Immunotherapies |
| Molecular Loop Biosciences | Woburn | MA | NGS Technology |
| Moma Therapeutics | Cambridge | MA | Enzymes - Molecular Machines |
| Monarch Biosciences | Charlestown | MA | Cell Therapy |
| Monopteros Therapeutics | Boston | MA | Oncology Small Molecule |
| Morphic Therapeutic | Waltham | MA | Oral Integrin Drugs |
| Mossman Associates | Milford | MA | Diagnostic products for infectious disease and drug abuse |
| Mouse Specifics | Framingham | MA | Lab Animal Gait Analysis |
| Multiply Labs | Cambridge | MA | Robotics for Cell Therapy Manufacturing |
| Mustang Bio | Worcester | MA | Immunotherapies |
| Myeloid Therapeutics | Cambridge | MA | Cell Therapy for Cancer |
| Myomo | Cambridge | MA | Arm brace to support and move weak arm |
| Myrtelle | Wakefield | MA | Gene Therapy |
| Mythic Therapeutics | Waltham | MA | Antibody-Drug Conjugates |
| Mytide Therapeutics | Boston | MA | Peptide Manufacturing Platform |
| N2 Biomedical | Bedford | MA | Implant Coatings |
| Nanobiosym | Cambridge | MA | Nanobiotech |
| NanoDx | Southborough | MA | Concussion diagnosis |
| NanoFUSE Biologics | Malden | MA | Bioactive glass combined with DBM |
| NanoMosaic | Woburn | MA | Nanoneedle-powered protein screening |
| Nanopath | Cambridge | MA | Molecular Diagnostics for Women |
| Naveris | Natick | MA | Cancer Diagnostic |
| Navigation Sciences | Brookline | MA | Surgical Navigation |
| Navitor Pharmaceuticals | Cambridge | MA | Drug discovery related to central metabolic signaling pathways |
| ndd Medical Technologies | Andover | MA | Lung Diagnostics Devices |
| NED Biosystems | Cambridge | MA | Oral combination cancer therapies |
| Neo Scientific | Cambridge | MA | Peptide Synthesis |
| Neovii Biotech | Lexington | MA | Stem Cell Therapy, Biologics |
| Nephrogen | Beverely | MA | Gene Therapy for Kidney Disease |
| Nereid Therapeutics | Cambridge | MA | Small molecules that can modulate protein interactions found in disease states |
| Nested Therapeutics | Cambridge | MA | Non-degrading, molecular |
| Neumora Therapeutics | Watertown | MA | Precision Medicines for Brain Diseases |
| NeurAegis | Southborough | MA | Neurodegenerative Treatments |
| NeuroBo Pharmaceuticals | Boston | MA | CNS & Diabetic Neuropathic Pain Treatments |
| NeuroDex | Natick | MA | Brain Diagnostics |
| Neurofix | Acton | MA | Small molecule for neurological conditions |
| Neurogastrx | Woburn | MA | Functional and motility gastrointestinal disorders |
| NeuroMetrix | Woburn | MA | Device Delivering Pain Relief |
| Neuroptika | Cambridge | MA | Regenerative Treatments for Ophthalmic Diseases |
| NeuroVasc Preclinical Services | Lexington | MA | Preclinical animal models & contract research |
| Neutrolis | Cambridge | MA | Enzyme Analogue Inflammation Treatment |
| Neutron Therapeutics | Danvers | MA | Boron Neutron Capture Therapy |
| New Amsterdam Genomics | Cambridge | MA | AI platform for genetics |
| New England Biolabs | Ipswich | MA | Reagents, Enzymes, Purification |
| New Equilibrium Biosciences | Cambridge | MA | Computational–experimental platform to discover lead drug candidates that regulate intrinsically disordered proteins implicated in cancers and neurodegenerative |
| New Health Sciences (NHS) Manufacturing | Avon | MA | Contract Medical Device Manufacturing |
| New Paradigm Biosciences | Woburn | MA | Human immune system mice for antibody-drug discovery |
| New View Surgical | Boston | MA | Imaging & Access Technologies |
| Nexcelom Bioscience | Lawrence | MA | Cell counters |
| Nextcea | Woburn | MA | Drug development service company |
| Nimbus Therapeutics | Cambridge | MA | Computer-Based Drug Discovery |
| Nirogy Therapeutics | Natick | MA | Tumor-targeting Small Molecules |
| Nitto Denko Avecia | Milford | MA | Oligonucleotide Manufacturing |
| Nitto Denko Avecia | Marlborough | MA | Oligonucleotide Manufacturing |
| Nocion Therapeutics | Waltham | MA | Nocions which preferentially target activated sensory neurons that are responding to external insult |
| NodThera | Lexington | MA | NLRP3 inflammasome inhibitors |
| NonExomics | Beverly | MA | Mining novel disease-associated proteins from the entire human genome |
| Nova Biomedical | Waltham | MA | Sample Analyzers |
| NovaBioAssays | Woburn | MA | Mass Spec Services |
| NovaBiotics | Boston | MA | Anti-Infectives |
| NovaLead Pharma | Shrewsbury | MA | Small Molecules |
| Novaliq | Cambridge | MA | Drug Delivery |
| Novartis | Cambridge | MA | Small Molecules, Vaccines, Biologics / Diagnostics |
| Novaseek Research | Cambridge | MA | Clinical Data Network for Research |
| Novateinbio | Woburn | MA | Proteins and antibodies, assay kits, contract research |
| Novellus Therapeutics | Cambridge | MA | Gene Editing Therapy |
| Novilla Pharmaceuticals | Cambridge | MA | Drug delivery technology for local administration of pain relief |
| NovoBiotic Pharmaceuticals | Cambridge | MA | Small Molecules |
| Novopyxis | Cambridge | MA | Transdermal drug delivery system |
| Novum Medical | Woburn | MA | Novel biomaterials to design innovative orthopedic implants |
| NuCana | Newton | MA | Chemotherapy |
| numares | Boston | MA | Clinical Diagnostics |
| NuProbe | Cambridge | MA | Nucleic Acid Profiling & Diagnosis |
| Nuvalent | Cambridge | MA | Structure-based Drug Design for Kinase Targeting |
| NxStage | Lawrence | MA | Medical Devices |
| Oak Hill Bio | Cambridge | MA | Small Molecules for Protein Misfolding diseases |
| ObsEva | Boston | MA | Therapies for pre-term labor |
| Obsidian Therapeutics | Cambridge | MA | Cell & Gene Therapies |
| OCT Group | Cambridge | MA | Clinical Research |
| Octagon Therapeutics | Cambridge | MA | Antibiotics |
| Ocular Therapeutix | Bedford | MA | Sustained ophthalmic therapies with proprietary tailored hydrogels |
| OcuTerra | Boston | MA | Diabetic Eye Disease Treatment |
| Olaris Therapeutics | Waltham | MA | Biomarker Response Technology |
| Oligo Factory | Holliston | MA | DNA, RNA Production |
| Olink Proteomics | Watertown | MA | Protein & Nucleic Acid Analysis |
| Omega Therapeutics | Cambridge | MA | Gene Editing |
| Omixon | Cambridge | MA | Next-gen sequencing products |
| OmniGuide | Lexington | MA | Surgical technology |
| OncoPep | North Andover | MA | Cancer vaccine |
| Oncorus | Cambridge | MA | Oncolytic Virus Cancer Immunotherapy |
| Oncovision | Boston | MA | Medical Imaging Machines |
| OncXerna Therapeutics | Waltham | MA | Cancer Therapeutics |
| Opko Health | Woburn | MA | Biologics, Vaccines, Diagnostics, etc. |
| Ora Clinical | Andover | MA | Ophthalmology Clinical Research |
| OraChrom | Woburn | MA | HPLC Columns |
| Orchard Therapeutics | Boston | MA | Ex-vivo autologous hematopoietic stem cell gene therapy |
| Organix | Woburn | MA | Contract Research & Development |
| Organogenesis | Canton | MA | Biologics |
| Orionis Biosciences | Waltham | MA | Small Molecules, Biologics |
| Orna Therapeutics | Cambridge | MA | oRNA, Delivery |
| Oryzon Genomics | Cambridge | MA | Biomarker Identification, Drugs |
| OSSIO | Woburn | MA | Bone growth fiber |
| Ovation.io | Cambridge | MA | LIMS |
| Ovid Therapeutics | Cambridge | MA | Treatments for rare brain disorders |
| Oxeia Biopharmaceuticals | Boston | MA | Concussion drug treatments |
| PackGene | Worcester | MA | Customized AAV vector cloning/packaging services |
| Palleon Pharmaceuticals | Waltham | MA | Glycoimmune Checkpoint Inhibitors |
| PamGene | Cambridge | MA | Microarray Equipment, Chips |
| PanTher Therapeutics | Cambridge | MA | Treatment of inoperable locally advanced solid tumors |
| PAQ Therapeutics | Cambridge | MA | Restoring health and curing disease through autophagy |
| Paragonix Technologies | Cambridge | MA | Organ Transport System |
| Paratek Pharmaceuticals | Boston | MA | Small Molecules |
| Paraza Pharma | Cambridge | MA | Concept to candidate drug discovery organization. Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise specializing in early stage Biotech start-ups. Contact us today at: info@parazapharma.com. On the web at: https://parazapharma.com |
| Parexel | Waltham | MA | Clinical Research |
| Partner Therapeutics | Lexington | MA | Biologics |
| PathMaker Neurosystems | Boston | MA | Neurostimulation therapy |
| PEAR Therapeutics | Boston | MA | Digital applications in concert with existing medicines |
| Peptech | Bedford | MA | Chemistry Services |
| PerkinElmer | Waltham | MA | Biotech Lab Supplies |
| PerkinElmer | Hopkinton | MA | Automation, Liquid Handling, Imaging, Reagents |
| Perthera | Holliston | MA | AI Cancer Therapy Determination |
| Pfizer | Andover | MA | Small Molecules, Vaccines, Biologics |
| Pfizer | Cambridge | MA | Small Molecules, Biologics |
| PhagePro | Somerville | MA | Bacteriophage-based |
| Pharmaessentia | Burlington | MA | Biologics |
| PharmaLex | Burlington | MA | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Pharmasol | South Easton | MA | CDMO |
| Phio Pharmaceuticals | Marlborough | MA | RNAi |
| Phoenix Tissue Repair | Boston | MA | Protein-replacement Therapy |
| Phosphorex | Hopkinton | MA | Nanospheres for drug delivery |
| Physical Sciences | Andover | MA | Retinal Imaging |
| PIC Therapeutics | Natick | MA | Modulating Oncology Translation to Improve Cancer Outcomes |
| Pieris Pharmaceuticals | Boston | MA | Modified Anticalins |
| Pillar Biosciences | Natick | MA | Targeted next-generation sequencing (NGS)-based assays and software |
| PineTree Therapeutics (2) | Cambridge | MA | Antibody Therapy, Virus-Targeting Recombinant Agent |
| Pinteon Therapeutics | Newton Centre | MA | Therapeutics targeting PIN-1 |
| Pion | Billerica | MA | Dissolution Data |
| PionEar Technologies | Allston | MA | Ear Tube Implant |
| Podimetrics | Somerville | MA | Diabetic Foot Ulcer Detection |
| Portal Instruments | Cambridge | MA | Needle-free drug delivery platform |
| Praxis Precision Medicines | Cambridge | MA | Genetic Neuroscience Treatments |
| Precision Stability Storage | Hopedale | MA | Biostorage, Pharma Stability Storage |
| Predictus BioSciences | West Roxbury | MA | Molecular Diagnostics |
| Pretzel Therapeutics | Waltham | MA | Mitochondrial Therapeutics |
| Prime Medicine | Cambridge | MA | Gene Editing Technology |
| Privo Technologies | Peabody | MA | Nano-engineered treatments |
| Promakhos Therapeutics | Allston | MA | Drugs for inflammatory disorders |
| PROMETRIKA | Cambridge | MA | Contract Clinical Work |
| Proof Diagnostics | Cambridge | MA | POC Covid test |
| ProQR Therapeutics | Cambridge | MA | Oligonucleotide Therapy |
| Protein Dynamic Solutions | Wakefield | MA | Protein Characterization for Drug Development |
| ProterixBio | Billerica | MA | Disease management platforms |
| Proterris | Boston | MA | Carbon Monoxide Therapy |
| Provia Labs | Littleton | MA | Biobanking, specifically dental |
| Psy Therapeutics | Boston | MA | CNS Treatments |
| Pulmatrix | Lexington | MA | Inhalable Aerosols |
| PureTech Health | Boston | MA | Brain, Immune, Gut axis |
| Pyramid Biosciences | Waltham | MA | TRK Modulators |
| Pyxis Oncology | Cambridge | MA | Antibody Immunotherapy |
| Q-State Biosciences | Cambridge | MA | Precision Genetic Medicine Services |
| Q32 Bio | Cambridge | MA | Biologics to restore healthy immune regulation |
| Qlaris Bio | Wellesley | MA | Ocular Small Molecules |
| Qlibrium | Woburn | MA | Bandage patch-like delivery pump |
| QSM Diagnostics | Boston | MA | Point-of-care diagnostics |
| QuantaBio | Beverly | MA | PCR equipment |
| Quanterix | Billerica | MA | Protein Quantification Technology |
| Quintara Bio | Cambridge | MA | DNA Sequencing |
| QurAlis | Cambridge | MA | ALS cure |
| Qynapse | Boston | MA | Imaging Analysis |
| Radius Health | Boston | MA | Small Molecules, Biologics |
| RAN biotechnologies | Beverly | MA | Chemicals |
| Ranfac Corp | Avon | MA | Marrow/Tissue sampling, Catheters, Biopsy Needles, etc |
| Ranok Therapeutics | Waltham | MA | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| Rapid Micro Biosystems | Lowell | MA | Microbial Analysis |
| Ras Labs | Boston | MA | Electroactive polymers for synthetic muscles |
| Ratio Therapeutics | Boston | MA | Radiotherapeutics |
| Rational Vaccines | Woburn | MA | Herpes Vaccine |
| Rectify Pharma | Cambridge | MA | Disease-modifying precision therapeutics for patients with serious genetic diseases |
| Rediscovery Life Sciences | Cambridge | MA | Drug Repurposing |
| ReForm Biologics | Woburn | MA | Excipients for Biologics |
| Regenacy Pharmaceuticals | Waltham | MA | Small Molecules |
| Regeneris Medical | North Attleboro | MA | Stem cell therapies for orthopedics, aging, sexual wellness |
| Relay Therapeutics | Cambridge | MA | Motion-based Drug Design |
| Remix Therapeutics | Cambridge | MA | Small molecule therapies designed to reprogram RNA processing |
| RenalGuard Solutions | Milford | MA | Contrast Dye-removal Device |
| Renovia | Boston | MA | Therapeutics/Diagnostics for Pelvic Floor Disorders |
| Repare Therapeutics | Cambridge | MA | Synthetic Lethal Therapeutics |
| Repertoire Immune Medicines | Cambridge | MA | Cell & Peptide-Based Therapies |
| Repligen | Waltham | MA | Protein Manufacturing |
| Replimune | Woburn | MA | Oncolytic immunotherapy |
| Reprieve Cardiovascular | Milford | MA | Heart Failure Device |
| ReproSource | Marlborough | MA | Fertility Testing |
| Resilience | Boston | MA | Biomanufacturing |
| Resilience | Waltham | MA | Biomanufacturing |
| Respiratory Motion | Watertown | MA | Respirator Depression Monitor |
| RevBio | Lowell | MA | Biocompatible Bone Adhesive |
| Reveal Pharmaceuticals | Cambridge | MA | Gadolinium-free MRI contrast agent |
| Revere Pharmaceuticals | Boston | MA | Small Molecules Targeting Rac1 signaling |
| Reverie Labs | Cambridge | MA | Brain-penetrant cancer therapies |
| Revitope Oncology | Cambridge | MA | Antibody conjugated to a peptide containing a protease cleavable site |
| ReviveMed | Cambridge | MA | AI-Driven Drug Discovery using Metabolomics |
| ReWalk Robotics | Marlborough | MA | Personal Exoskeleton |
| Rgenta Therapeutics | Cambridge | MA | RNA-targeting medicines |
| rhealth | Bedford | MA | Diagnostics |
| Rhythm Pharmaceuticals | Boston | MA | Peptide Therapeutics |
| Ribon Therapeutics | Cambridge | MA | Cancer drugs that target specific types of poly ADP-ribose polymerase |
| Rilas Technologies | Woburn | MA | Purification & Analytical Solutions |
| Ring Therapeutics | Cambridge | MA | Gene Therapy Targeting the Human Commensal Virome |
| Riparian Pharmaceuticals | Watertown | MA | Vascular-derived therapies |
| Rizana Therapeutics | Quincy | MA | Treatments for Drug Addiction |
| ROME Therapeutics | Cambridge | MA | Drugging Junk DNA |
| ROMEG Therapeutics | Woburn | MA | Plant originated solutions for every day ailments |
| RootPath Genomics | Watertown | MA | Personalized T Cell Therapy Platform |
| RSB SPINE | Norwell | MA | Spinal Fusion Device |
| Rubik Therapeutics | Cambridge | MA | Cell Therapies for Solid Tumors |
| Rubix Life Sciences | Lawrence | MA | Contract Research & Services |
| Safecor Medical | Woburn | MA | Contract drug and medical device packaging/kitting services |
| SafeRx Pharmaceuticals | Lenox | MA | Alcohol-resistant Opioid |
| Sage Science | Beverly | MA | DNA Fractionation |
| Sage Therapeutics | Cambridge | MA | Small Molecules for CNS Disorders |
| SalioGen Therapeutics | Burlington | MA | Gene Therapy Platform Technology |
| Salzman Group | Beverly | MA | Drug Discovery Contract Work |
| SanaRx Biotherapeutics | Allston | MA | |
| Sanguine Biosciences | Waltham | MA | Clinical Trial Specimen Collection |
| Saniona | Waltham | MA | Small Molecules |
| SANO Diagnostics | Wellesley Heights | MA | Inflammation Detection |
| Sanofi | Waltham | MA | Small Molecules, Biologics |
| Sanofi | Cambridge | MA | Biologics, Vaccines |
| Santhera Pharmaceuticals | Burlington | MA | Orphan Neuromuscular Disease Targets |
| Sarepta Therapeutics | Cambridge | MA | Biologics |
| Sarepta Therapeutics | Andover | MA | Biologics |
| Satellite Bio | Cambridge | MA | Implantable satellite organs |
| Savran Technologies | Newton | MA | Non-invasive Diagnostics |
| SBH Sciences | Natick | MA | A pre-clinical CRO specializing in protein production, cell-based assays, and bio-marker analysis. |
| Scholar Rock | Cambridge | MA | Biologics |
| Schrodinger | Cambridge | MA | Computer-Based Drug Discovery |
| Sciex | Framingham | MA | Mass Spectrometers and Training |
| Scipher Medicine | Waltham | MA | Diagnostics for medicine suitability |
| SciSafe | Billerica | MA | Biostorage |
| Scitara Corporation | Marlborough | MA | Digital transformation and lab connectivity |
| Scorpion Therapeutics | Boston | MA | Small Molecules |
| scPharmaceuticals | Burlington | MA | Micropump & delivery system |
| SDC | Waltham | MA | Clinical Data Services |
| Seismic Therapeutics | Watertown | MA | Bispecific therapeutic antibodies |
| Sekisui Diagnostics | Burlington | MA | Diagnostics |
| Selecta Biosciences | Watertown | MA | Immunogenicity Prevention in Biologic and Enzyme Therapy |
| SeLux Diagnostics | Charlestown | MA | Infectious Disease Phenotyping |
| Selvita | Cambridge | MA | Drug Discovery |
| Senda Biosciences | Cambridge | MA | Small Molecules Targeting Gut |
| Sentien Biotechnologies | Lexington | MA | Drug delivery during dialysis |
| Seqens CDMO North America | Newburyport | MA | Contract Manufacturing & Research |
| SeqLL | Woburn | MA | DNA / RNA Sequencing |
| SeQure Dx | Waltham | MA | Personalized Diagnostics for Gene Editing Therapies |
| seqWell | Beverly | MA | Sequencing Service |
| Seracare Life Sciences | Milford | MA | Biologic products for research |
| Serena Group | Cambridge | MA | Wound care and hyperbaric oxygen therapies |
| Seres Therapeutics | Cambridge | MA | Microbial drugs to counteract antibiotic side effects |
| SeromYx Systems | Cambridge | MA | Systems Serology |
| SHEPHERD Therapeutics | Natick | MA | Accelerated Treatments for Rare Cancers |
| Sherlock Biosciences | Cambridge | MA | Molecular Diagnostics |
| Sidereal Therapeutics | Boston | MA | First-in-class treatments for Acute Kidney Injury & Iron-Mediated Disorders |
| Siemens Healthineers | Norwood | MA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Sigilon Therapeutics | Cambridge | MA | Living Therapeutics |
| Signifier Medical Technologies | Needham | MA | Snoring Prevention Device |
| Sinaptica Therapeutics | Cambridge | MA | Noninvasive Neurostimulation Treatment for Alzheimer’s Disease |
| Sionna Therapeutics | Natick | MA | Small Molecule Targeting CF |
| Sirion Biotechnology | Cambridge | MA | Viral vector engineering, transduction enhancement and technology development |
| Skyhawk Therapeutics | Waltham | MA | RNA-correcting Small Molecules |
| SmartPharm Therapeutics | Cambridge | MA | Production of biologics within patients via gene therapy |
| Smith and Nephew | Andover | MA | Sports Medicine, Trauma, Wound Care, etc. |
| Sofregen Medical | Medford | MA | Silk-based for tissue defects |
| SOLA Biosciences | Natick | MA | Gene Therapies for Protein Misfolding Diseases |
| SOLABS | Framingham | MA | Enterprise Quality Management System Software |
| Solace Therapeutics | Framingham | MA | Bladder Control System |
| Solarea Bio | Cambridge | MA | Microbiome Treatments |
| Solid Biosciences | Cambridge | MA | Gene Therapy, Devices, Biologics, Small Molecules all for DMD |
| Sonde | Boston | MA | Voice-Based Diagnostics |
| SOPHiA GENETICS | Boston | MA | Clinical Next Gen Sequencing Dry Lab Service |
| SopReg Consulting | Sharon | MA | Regulatory Submission Consulting |
| SOTIO | Boston | MA | Active Cellular Immunotherapy |
| SpectraWAVE | Bedford | MA | Medical Imaging Platform |
| Spero Therapeutics | Cambridge | MA | Anti-infectives |
| Spirita Oncology | Natick | MA | Small Molecule for Cancer |
| SQZ Biotech | Watertown | MA | Cell therapies for multiple indications using their proprietary CellSqueeze platform |
| Stallergenes Greer | Boston | MA | Allergen Desensitization |
| Stargazer Pharmaceuticals | Boston | MA | Ophthalmology Treatment |
| STC Biologics | Newton | MA | Services |
| Stealth BioTherapeutics | Newton | MA | Mitochondrial disease therapies |
| StemCellerant | Cambridge | MA | Stem Cell Contract Research & Services, Stem Cell Therapy |
| Stoke Therapeutics | Bedford | MA | Antisense Oligonucleotide Medicines |
| Strand Therapeutics | Cambridge | MA | Gene Therapy |
| Strategia Therapeutics | Natick | MA | Acquisition & Accelerated Development |
| Straumann | Andover | MA | Dental Implants and Regeneration |
| STRM.BIO | Boston | MA | Extracellular vesicles (EVs) to deliver gene therapies |
| Sumitomo Dainippon Pharma Oncology | Cambridge | MA | RNAi, Small Molecules |
| Summit Therapeutics | Cambridge | MA | Utrophin modulation technology |
| Sunflower Therapeutics | Hingham | MA | Efficient biologics drug development platform |
| Sunovion | Marlborough | MA | Small Molecules |
| Suono Bio | Cambridge | MA | Ultra-rapid delivery of novel therapeutics |
| Surface Oncology | Cambridge | MA | Cancer immunotherapies |
| SURGE Therapeutics | Cambridge | MA | Intraoperative Immunotherapy to Improve Survival Outcomes Post-Surgery |
| Surgicure Technologies | Cambridge | MA | Intubation |
| Swedish Orphan Biovitrum | Waltham | MA | Biologics |
| Syd Labs | Hopkinton | MA | Antibodies, reagents, research supplies, etc. |
| Sygnature Discovery | Cambridge | MA | Drug Discovery Contract Research |
| Symbiosis Pharmaceutical Services | Cambridge | MA | Symbiosis provides fill/finish manufacturing slots with expertise of vaccines, mAbs and more, offering integrated services to get drug products from manufacture to release. |
| Syndax Pharmaceuticals | Waltham | MA | Tumor Phenotype Modification |
| SynDevRx | Cambridge | MA | Polymer conjugate |
| Syner G Pharma Consulting | Southborough | MA | CMC Consulting |
| Synlife | Kendall | MA | Synthetic Cells |
| Synlogic | Cambridge | MA | Synthetically engineered, therapeutic microbes |
| Synspira Therapeutics | Framingham | MA | Inhaled glycopolymer-based therapeutics for the treatment of pulmonary disease |
| Syros Pharmaceuticals | Cambridge | MA | Gene Regulation Drug Discovery Platform |
| SYTE.bio | Newton | MA | Precision therapeutics using its proprietary Linear DNA and Circular RNA technology platforms |
| T2 Biosystems | Lexington | MA | Diagnostics |
| Takeda | Cambridge | MA | Small Molecule, Enzymes |
| Takeda | Lexington | MA | Small Molecule, Enzymes |
| Talaris Therapeutics | Wellesley | MA | Improved Transplantation |
| Talem Therapeutics | Cambridge | MA | Acquisition of drug product candidates |
| Tango Therapeutics | Cambridge | MA | Cancer Therapeutics, Immuno-Oncology |
| TCR2 Therapeutics | Cambridge | MA | T Cell Immunotherapy |
| TE Connectivity | Watertown | MA | Catheter manufacturing & development |
| TearClear | Boston | MA | Ophthalmic Drug Delivery |
| Tecomet | Wilmington | MA | Implant Components |
| Tectonic Therapeutic | Allston | MA | GPCR Targeting Drugs |
| Tegra Medical | Franklin | MA | Contract Medical Device Manufacturer |
| TellBio | Beverly | MA | Liquid Biopsy Platform |
| Tenza | Cambridge | MA | Reprogramming symbiotic bacteria from the human microbiome to administer medicines directly to the organs they naturally inhabit |
| TeraRecon | Acton | MA | Advanced image processing |
| Terumo Cardiovascular Systems | Ashland | MA | Medical Devices |
| Tessera Therapeutics | Cambridge | MA | Gene Writing |
| Tetraphase Pharmaceuticals | Watertown | MA | Antibiotic Small Molecules |
| Tevard Biosciences | Cambridge | MA | tRNA-based Gene Therapies |
| The Windshire Group | Woburn | MA | CMC Consulting |
| TheraCell | Littleton | MA | Regenerative Medicine, Bone Grafts |
| Theracos | Marlborough | MA | Small Molecules |
| Theragnostics | Boston | MA | Radiopharmaceuticals |
| Thermedical | Waltham | MA | Thermal Ablation Therapy |
| Thermo Fisher | Waltham | MA | Lab Supplies and Equipment |
| Thermo Fisher | Tewksbury | MA | Medical Diagnostics, Counterfeit Detection |
| Theromics | Bridgewater | MA | Tissue Ablation |
| Theseus Pharmaceuticals | Cambridge | MA | Kinase Inhibitors |
| Third Harmonic Bio | Cambridge | MA | Allergy & Inflammation Treatments |
| Third Pole Therapeutics | Waltham | MA | Inhaled NO Delivery System |
| Thrive Bioscience | Wakefield | MA | Analytical & automation technology |
| Thrombolytic Science International | Cambridge | MA | Stroke drug |
| Thymmune Therapeutics | Cambridge | MA | Thymic engineering platform and cell therapies |
| Tiba Biotech | Cambridge | MA | RNA Vaccine Platform |
| Tissue Vision | Newton | MA | Biomedical Imaging & Tissue Processing |
| Torus Biosystems | Cambridge | MA | Diagnostics |
| TransCode Therapeutics | Allston | MA | RNA Delivery, Small Molecule |
| Transgene | Boston | MA | Viral Vector Therapeutics, Gene Therapy |
| Transition Bio | Cambridge | MA | Condensate technology, liquid-liquid phase separation |
| TransMedics | Andover | MA | Heart & Lung Preservation Machines |
| Transplant Genomics | Mansfield | MA | Monitoring to prevent transplant rejection |
| TreeFrog Therapeutics | Boston | MA | 3D Stem Cell Culture Technology |
| Treeline Biosciences | Watertown | MA | Molecular targets in oncology that are validated but difficult to drug |
| Tremeau Pharmaceuticals | Concord | MA | Non-opioid pain therapies |
| Trevie Research | Cambridge | MA | Clinical development advisory and trial management services focused in oncology |
| Triana Biomedicines | Waltham | MA | Platform to discover and develop molecular glues - E3 ubiquqitin ligases |
| TriNetX | Cambridge | MA | Clinical Data Management Software |
| TScan Therapeutics | Waltham | MA | T Cell Therapies |
| Twentyeight-Seven Therapeutics | Watertown | MA | Small Molecules to Target ncRNA Biology |
| Ultivue | Cambridge | MA | Reagents, chemicals |
| Unchained Labs | Woburn | MA | Tools for biologics research & development |
| Unicus Pharmaceuticals | Taunton | MA | Contract R&D services; Topical and Oral Semisolids, Solutions & Suspensions; Drug Delivery |
| uniQure | Lexington | MA | Gene Therapy |
| United States Biological | Salem | MA | Antibodies, Lab Supplies |
| Upstream Bio | Waltham | MA | Therapies for allergic, inflammatory conditions |
| Valence Discovery | Cambridge | MA | AI-Enabled Drug Design |
| Valo Health | Lexington | MA | Drug Discovery & Development Engine |
| Variantyx | Framingham | MA | Clinical Diagnostic Services |
| Vaxess Technologies | Cambridge | MA | Silk Protein Technology for biologic stabilization |
| Vaxxas | Cambridge | MA | Vaccine patch delivery system |
| VBI Vaccines | Cambridge | MA | Vaccine Development |
| Vedanta Biosciences | Cambridge | MA | Therapies that modulate pathways of interaction between the human microbiome and the host immune system |
| VenoStent | Boston | MA | External vein stent |
| Ventus Therapeutics | Waltham | MA | Small Molecules targeting proteins in the inflammasome and nucleic acid sensing signaling pathways |
| Verastem Oncology | Needham | MA | Drugs Targeting Cancer Stem Cells |
| Verax Biomedical | Marlborough | MA | Transplantation Screening |
| Vericel | Cambridge | MA | Cellular Therapy |
| Veristat | Southborough | MA | Veristat is a full-service CRO with expertise in regulatory strategy, clinical trial design and implementation, data analysis and preparation of marketing applications. We specialize in supporting biopharma developing the most complex novel, rare, and advanced therapies. " |
| Versatope Therapeutics | Lowell | MA | Exosomes derived from probiotics |
| Verseau Therapeutics | Bedford | MA | Macrophage checkpoint modulators |
| Vertex | Boston | MA | Small Molecules |
| Vertex | Cambridge | MA | Small Molecules |
| Verve Therapeutics | Cambridge | MA | Gene-editing Treatments |
| Vesigen Therapeutics | Cambridge | MA | Fusogenic extracellular vesicle delivery technology |
| ViaCord | Cambridge | MA | Cord Blood Banking |
| Viant Medical | Foxborough | MA | Contract Medical Device Manufacturer |
| Viant Medical | Wilmington | MA | Contract Medical Device Manufacturer |
| Vibalogics | Boxborough | MA | Contract Vaccines |
| Vicarious Surgical | Waltham | MA | Surgical Robotics |
| Vigeo Therapeutics | Cambridge | MA | Biologics for Cancer |
| Vigil Neuroscience | Cambridge | MA | Microglia-based Therapeutics for Neurodegenerative Diseases |
| Vincere Biosciences | Cambridge | MA | Small Molecules to Target Parkinson's |
| Viridian Therapeutics | Waltham | MA | MicroRNA |
| Virna Therapeutics | West Roxbury | MA | Neutralizing Monoclonal Antibody |
| Virtech Bio | Natick | MA | Therapies for organ and tissue preservation, ex vivo organ management and biomarker discovery, HBOC |
| VITRAC Therapeutics | Boston | MA | |
| Vivonics | Bedford | MA | Intracranial Pressure and Assessment Screening System |
| Vivtex | Cambridge | MA | Oral Biologic Delivery |
| Vizgen | Cambridge | MA | Next-generation spatially resolved, single-cell transcriptomics |
| Volta Labs | Cambridge | MA | Genomic Sample Prep Technolgy |
| Vor Biopharma | Cambridge | MA | CAR-T Stem Cell Therapy |
| Voyager Therapeutics | Cambridge | MA | AAV capsid Gene Therapy |
| Vuja De Sciences | Natick | MA | Cancer |
| Walden Biosciences | Cambridge | MA | Podocyte-targeting Kidney Disease Treatments |
| Waters | Milford | MA | Chromatography & Chemistry |
| WaVe Life Sciences | Cambridge | MA | Nucleic acid therapies |
| Welgen | Worcester | MA | Viral Services |
| Wellesley Pharmaceuticals | Newton | MA | Acetaminophen/Ibuprofen combo |
| Werewolf Therapeutics | Cambridge | MA | Cancer Treatments |
| Whale Imaging | Waltham | MA | Ultrasound, Surgical Imaging |
| Windgap Medical | Watertown | MA | Long-term stable epinephrine Injection |
| WntRx Pharmaceuticals | Worcester | MA | Novel inhibitors of beta-catenin |
| WorldCare Clinical | Boston | MA | Imaging cro, therapeutics area expertise, & endpoint adjudication committees |
| Worldwide Clinical Trials | Cambridge | MA | Clinical Research |
| Wyzer Biosciences | Cambridge | MA | Sanger sequencing |
| X-Biotix Therapeutics | Waltham | MA | Publishing Research on Small Molecule for MDR gram negative pathogens |
| X-Chem Pharmaceuticals | Waltham | MA | Small molecule drug discovery |
| X-Cor Therapeutics | Allston | MA | Extracorporeal CO2 removal device |
| X4 Pharmaceuticals | Boston | MA | Oral small molecules |
| Xenetic Biosciences | Framingham | MA | Biologic drugs, novel oncology therapeutics and vaccinations |
| Xilio Therapeutics | Waltham | MA | Cancer Immunotherapies |
| XP Pharma Consulting | Cambridge | MA | Drug Development Consulting |
| XtalPi | Cambridge | MA | AI Drug Design |
| YMC Process Technologies | Devens | MA | Purification Technology |
| Yumanity Therapeutics | Boston | MA | Protein misfolding conditions |
| Yurogen Biosystems | Boston | MA | Antibodies & Services |
| Zai Lab | Cambridge | MA | Small Molecules |
| Zata Pharmaceuticals | Worcester | MA | RNA, DNA Therapeutics |
| ZebiAI Therapeutics | Waltham | MA | Machine Learning Small Molecule Drug Discovery |
| Zepteon | Boston | MA | Isolation of Nonfucosylated Antibodies |
| ZeptoMetrix | Franklin | MA | Infectious Disease Diagnostics |
| Zeta Surgical | Boston | MA | Surgical Guidance Technology |
| Ziopharm Oncology | Boston | MA | Cellular Therapies |
| Zoll | Chelmsford | MA | Medical Devices, Defibrillators |
| Zoll | Chelmsford | MA | Medical Devices, Defibrillators |
| Zumutor Biologics | Cambridge | MA | Biologics |
| Zyno Medical | Natick | MA | Infusion Pumps |
| 149 Medical | Worcester | MA | Non- invasive real- time cerebral blood flow device |
| Antigen Targeting Consulting | Worcester | MA | Antibody production & services |
| Eascra Biotech | Boston | MA | mRNA Delivery Platform |
| Entact Bio | Watertown | MA | Bifunctional molecules that recruit deubiquitinating enzymes to target proteins to remove ubiquitin |
| Rejoni | Bedford | MA | Hydrogel for Uterine Surgery |
| NextPoint Therapeutics | Cambridge | MA | Antibody Therapies |
| AssayQuant | Marlborough | MA | Fluorescence Microplate Assays |
| Gensaic | Cambridge | MA | Phage-derived Particles for Gene Delivery |
| MedTherapy Biotechnology | Quincy | MA | Cell, Gene & Immunotherapies for Cancer |
| Pepper Bio | Boston | MA | Transomics drug discovery |
| SanegeneBio | Woburn | MA | siRNA Drug Discovery |
| Isterian Biotech | Boston | MA | Small molecule inhibitors of transglutaminase 2 |
| Velsera | Charlestown | MA | Biomedical data analysis platform |
| Cell BioEngines | Boston | MA | Cell-based Immunotherapies |
| LAPIX Therapeutics | Boston | MA | On-Off Immunity Treatments |
| Regel Therapeutics | Cambridge | MA | AAV gene delivery |
| Aera Therapeutics | Boston | MA | Genetic Medicines |
| Cell Mosaic | Woburn | MA | Bioconjugation Tools |
| CG Scientific | Worcester | MA | Cell Manufacturing Automation Solutions |
| CMO partners | Billerica | MA | Contract development and manufacturing |
| Conagen | Bedford | MA | Microbial Production |
| HBM Alpha Therapeutics | Cambridge | MA | Antibody Therapeutics |
| InnDura Therapeutics | Cambridge | MA | Next-Generation Paradigm for Armed Memory-Like Innate Immune Cell Therapies |
| Innovo Bioanalysis | Mansfield | MA | Analytical Services |
| Kano Therapeutics | Cambridge | MA | Design and engineering of novel genetic vectors |
| Nanite | Boston | MA | AI-driven polymer design platform focused on next-generation, non-viral gene delivery |
| Psivant | Boston | MA | Physics-driven Drug Design |
| Transmural Systems | Andover | MA | Electrosurgical transcatheter guidewire system |
| Via Scientific | Cambridge | MA | Multi-omics Platform |
| Advamedica | Cambridge | MA | Biomaterial based medical devices for pre-hospital, intra-operative and post-operative clinical needs |
| Aldena Therapeutics | Boston | MA | siRNA-based therapies for dermatological therapies |
| Ampersand Biomedicines | Cambridge | MA | Programmable medicines |
| Covant Therapeutics | Boston | MA | Covalent small molecules targeting post-translational modification sites |
| Droplet Biosciences | Cambridge | MA | Non-invasive liquid lymph biopsy |
| Rapport Therapeutics | Boston | MA | Precision medicines for neurological disorders |
| Watershed Informatics | Cambridge | MA | Bioinformatics Software |
| 76Bio | Boston | MA | Targeted Protein Degraders |
| Amasa Therapeutics | Boston | MA | Cell Therapy for Cancer |
| Arvada Therapeutics | Brookline | MA | |
| Bilayer Therapeutics | Cambridge | MA | Bile acid delivered via proprietary bilayer tablet technology |
| Carepoint Solutions | Beverly | MA | Bile acid delivered via proprietary bilayer tablet technology |
| Certego Therapeutics | Boston | MA | Psychiatric disorder therapies |
| CILA Therapeutics | Boston | MA | Inhaled therapies for the treatment of Primary Ciliary Dyskinesia |
| Convergent Therapeutics | Boston | MA | Radiotherapies |
| Corza Medical | Westwood | MA | Surgical Devices |
| Courage Therapeutics | Newton | MA | Eating Disorder Treatments |
| Edelweiss Immune | Cambridge | MA | |
| Enable Life Sciences | Cambridge | MA | Pharma Consulting |
| Fornax Biotech | Worcester | MA | Next-Gen Sequencing |
| Matice Biosciences | Cambridge | MA | Peptides for Scar Reduction |
| MedTherapy Biotech | Quincy | MA | Cell, gene & Immunological Therapies |
| Metro Biotech | Worcester | MA | NAD+ Pharmaceuticals |
| Nemucore Medical Innovations | Wellesley | MA | Cancer Therapies |
| NyLa Laboratories | Worcester | MA | |
| Oncovolution | Mansfield | MA | Platinum-based chemotherapies |
| Pharma Models | Marlborough | MA | Preclinical CRO |
| PraNa Biosciences | Worcester | MA | Biologics |
| Precision Biosystems | Mansfield | MA | Western blot automation |
| ProFoldin | Hudson | MA | Biochemical Assays |
| Pulsar Bio | Watertown | MA | DNA Encoded library assays |
| Resonance Medicine | Cambridge | MA | Drug Development |
| SignaBlok | Shrewsbury | MA | Mechanism-based targeted therapeutics and delivery nanosystems |
| Sisu Pharma | Boston | MA | Compounds Targeting HSF1 |
| Snap Dragon Chemistry | Waltham | MA | Process Development & Manufacturing for Fine Chemical Pharmaceuticals |
| Stylus Medicine | Boston | MA | Therapeutics |
| SynerK | Concord | MA | RNA-targeted Therapies |
| tBrexa | Mansfield | MA | B Reg cells |
| Theranano | Newton | MA | Drug-releasing implants |
| Vrata Therapeutics | Cambridge | MA | Precision medicines |
| ZSFab | Boston | MA | 3D printed surgical implants |