Philadelphia, the birthplace of cell and gene therapy, is a fast-growing biotech and biopharma cluster. Biotech companies in Philadelphia and the greater Delaware area are growing and merging for further research, innovations and collaborations.
We’re pleased to provide our readers with this comprehensive directory of life science companies in Greater Philadelphia/Delaware Valley. To learn more about these local businesses, simply search by company name or find alphabetically or by location or business. These listings are provided courtesy of BioPharmGuy, the premier resource for worldwide biotech company data.
To add your company, update information, or to highlight your company in the Big4Bio:Philadelphia newsletter, please contact us at info@big4bio.com.
| Company Name | City | State | Business |
|---|---|---|---|
| 3Sixty Pharma Solutions | Conshohocken | PA | Services & Consulting |
| Abbott | Princeton | NJ | Diagnostics |
| Absorption Systems | Exton | PA | Preclinical Testing |
| Abzena | Bristol | PA | Contract Development - Biologics |
| Abzyme Therapeutics | Royersford | PA | Modular single domain VHH antibody fragments for immunotherapy |
| Accutome | Malvern | PA | Ophthalmic Diagnostic Equipment |
| ACI Clinical | Bala Cynwyd | PA | Clinical Research |
| Acino | Hamilton Township | NJ | Novel drug delivery formulations |
| Aclaris Therapeutics | Wayne | PA | Novel topical dermatological therapies |
| Aclipse Therapeutics | Radnor | PA | Small Molecules |
| ACROBiosystems | Newark | DE | ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics, vaccines, and diagnostics. |
| Acrotech Biopharma | East Windsor | NJ | Specialty Pharmaceuticals |
| Actinobac Biomed | Kendall Park | NJ | Biologics |
| Adaptimmune Therapeutics | Philadelphia | PA | T Cell Cancer Therapy |
| Adare Pharma Solutions | Lawrenceville | NJ | Contract development & manufacturing of generics, small molecules; Formulation Technology |
| Adesis | New Castle | DE | Custom Organic Synthesis |
| Advaxis | Princeton | NJ | Listeria Vaccine |
| Agile Therapeutics | Princeton | NJ | Women's Healthcare |
| Agilent | Wilmington | DE | Equipment |
| AIROS Medical | Audubon | PA | Compression Therapy Devices |
| Akros Pharma | Princeton | NJ | Clinical Research |
| Alamo Pharma Services | Doylestown | PA | Pharmaceutical Sales Services |
| AllerGenis | Hatfield | PA | Food Allergy Diagnostics |
| Allevi | Philadelphia | PA | 3D bioprinters |
| Alliance Pharma | Malvern | PA | Contract Research & Consulting |
| AlphaThera | Philadelphia | PA | Antibody Conjugation Technology |
| ALS Biopharma | Doylestown | PA | ALS therapies |
| American Regent | Norristown | PA | Contract Development, MFG |
| Amicus Therapeutics | Philadelphia | PA | Small Molecules |
| Amneal Pharmaceuticals | Fort Washington | PA | Small Molecules |
| Amring Pharmaceuticals | Berwyn | PA | Generics |
| Amyndas Pharmaceuticals | Philadelphia | PA | Peptide for various disorders |
| Analytical Biological Services | Wilmington | DE | Custom Bioreagents |
| Angle plc | King of Prussia | PA | Liquid Biopsy |
| Annovis Bio | Berwyn | PA | Specialty Pharmaceuticals for Parkinson's |
| ANP Technologies | Newark | DE | Immunogenicity Testing, Biotech Reagents, Contract Work |
| Anpac Bio | Ambler | PA | Cancer Differentiation Analysis |
| Antares Pharma | Ewing | NJ | Drug Delivery |
| AOIC | Exton | PA | Medical & scientific communications company |
| Apcer Life Sciences | Princeton | NJ | Consultants |
| Aprecia Pharmaceuticals | East Windsor | NJ | Zipdose formulation |
| ARKAY Therapeutics | East Windsor | NJ | Diabetes Treatment |
| Aro Biotherapeutics | Philadelphia | PA | Protein Scaffolds |
| ArriVent Biopharma | Newtown Square | PA | Small Molecule |
| Asana BioSciences | Lawrenceville | NJ | Small Molecule, Biologics |
| Aspire Bariatrics | Exton | PA | Stomach Emptying Weight Loss Device |
| AstraZeneca | Wilmington | DE | Small Molecules, Biologics |
| Atrin Pharmaceuticals | Doylestown | PA | Small Molecule for Oncology |
| AUM BioTech | Philadelphia | PA | RNA-silencing Products |
| AUM LifeTech | Philadelphia | PA | Gene silencing technology |
| Avantor Sciences | Radnor | PA | Lab Products & Chemicals |
| Avisa Diagnostics | Malvern | PA | Breath Diagnostics |
| Avisi Technologies | Philadelphia | PA | Nanotechnology-enabled implant that controls intraocular pressure in the eye to treat open-angle glaucoma |
| Axonova Medical | Philadelphia | PA | Nerve Regeneration |
| Azzur | Hatboro | PA | Consulting |
| Baudax Bio | Malvern | PA | Specialty Pharma |
| Baugher Consulting | Philadelphia | PA | Pharmaceutical, Medical Device QA Consulting |
| Beta Pharma | Princeton | NJ | Small Molecules |
| Bilcare | Delaware City | DE | Pharma Packaging |
| Bioclinica | Princeton | NJ | Clinical Trial Solutions |
| Biocoat | Horsham | PA | Medical Device Coatings |
| BioDetego | Philadelphia | PA | Cancer Diagnostics |
| Biomatik | Wilmington | DE | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services. Biomatik.com: 10,000+ scientists served since 2002. Over 3,000 citing publications. |
| Biomeme | Philadelphia | PA | Portable real-time PCR |
| Bionpharma | Princeton | NJ | Generics |
| Biopeptek Pharmaceuticals | Malvern | PA | Peptides, CDMO |
| BioPharmaSpec | Malvern | PA | Amino Acid Sequencing, Contract Research |
| Biopticon | Princeton | NJ | Tumor Imaging |
| Bioquark | Philadelphia | PA | Regenerative Biologics |
| Bio-Rad | Philadelphia | PA | Tumor Markers |
| BioTelemetry | Malvern | PA | Remote Cardiac Monitoring |
| BioTillion | Skillman | NJ | Sample Tracking |
| BioWa | Princeton | NJ | Licensing company for parent |
| Bora CDMO | Wilmington | DE | Contract Development & Manufacturing |
| Botanix Pharmaceuticals | King of Prussia | PA | Novel, clinical-stage synthetic cannabinoid product pipeline for dermatology and antimicrobial indications |
| Braeburn Pharmaceuticals | Plymouth | PA | Out licensing |
| Bristol Myers Squibb | Pennington | NJ | Biologics Process Development |
| Bristol Myers Squibb | Princeton | NJ | Small Molecules, Biologics |
| Cabaletta Bio | Philadelphia | PA | Chimeric Auto Antibody Receptors |
| Caelum Biosciences | Bordentown | NJ | Antibody Therapy |
| Cagent Vascular | Wayne | PA | Balloon Catheter |
| Camber Spine | King of Prussia | PA | Spinal Implants |
| CaPtivate Pharmaceuticals | Doylestown | PA | Calcium Phosphate Nanoparticle vaccine adjuvant/delivery system |
| Carisma Therapeutics | Philadelphia | PA | CAR Macrophage Immunotherapy |
| CD Diagnostics | Claymont | DE | Joint Pain Diagnosis |
| Celerion | West Conshohocken | PA | Clinical Research |
| Cellgenemedix | Newark | NJ | Contract Manufacturing, Diagnostics |
| Celsion | Lawrenceville | NJ | Heat-Activated Liposomal Technology, Oncology |
| Center for Breakthrough Medicines | King of Prussia | PA | Cell Therapy Contract Research & Manufacturing |
| Centinel Spine | West Chester | PA | Spinal Implants |
| Century Therapeutics | Philadelphia | PA | iPSC Therapy platform |
| Certara | Princeton | NJ | Virtual Drug Screening |
| Cetylite Industries | Pennsauken | NJ | Formulation, packaging and distribution |
| Charles River Laboratories | Horsham | PA | Research Animal Models and Preclinical Research |
| Charles River Laboratories | Malvern | PA | Research Animal Models and Preclinical Research |
| Charles River Laboratories | Newark | DE | Research Animal Models and Preclinical Research |
| Chemical and Pharmaceutical Solutions | Hamilton Square | NJ | API Services |
| Chimeron Bio | Philadelphia | PA | Cancer Immunotherapy |
| China Chemical and Pharmaceutical Company | Exton | PA | APIs, Generics |
| Chip Diagnostics | Philadelphia | PA | Microfluidic Diagnostics |
| Chiral Technologies | West Chester | PA | Chromatography Products |
| Chromatan | Philadelphia | PA | Single-use, column-free purification |
| Churchill Pharmaceuticals | Princeton | NJ | Drug Delivery Technology |
| CiVi Biopharma | Conshohocken | PA | Novel therapies against cardiometabolic diseases |
| ClinChoice | Fort Washington | PA | Contract research - data management, biostatistics, clinical operations, regulatory, safety, pharmacovigilance, toxicology, medical affairs, medical writing, quality, risk, and compliance |
| Clinical Research of Philadelphia | Philadelphia | PA | Clinical Research |
| Clinlogix | Lower Gwynedd | PA | Clinical Research Management |
| ClinSmart | Newtowm | PA | Clinical Research |
| CloudLIMS | Wilmington | DE | Laboratory Information Management System software |
| Code Biotherapeutics | Hatfield | PA | DNA-based Gene Therapy Vector |
| Coeptis Pharmaceuticals | Wexford | PA | 505(b)(2) |
| Complexa | Berwyn | PA | Small Molecule |
| Complexa | Berwyn | PA | Small Molecule |
| Conifer Point Pharmaceuticals | Doylestown | PA | Computational chemistry services |
| Context Therapeutics | Philadelphia | PA | Treatments for hormone-driven cancers |
| Core Prognostex | Washington | NJ | Biospecimens |
| Corevigilance | Collegeville | NJ | Pharmacoviglance and consulting |
| Coriell Life Sciences | Philadelphia | PA | Genetic Analysis |
| CSL Behring | King of Prussia | PA | Biologics |
| CurAccel | Newtown | PA | Clinical Research Services |
| Cytel | King of Prussia | PA | Clinical software, statistical services |
| CytoSorbents | Monmouth Junction | NJ | Blood Purification Therapy |
| DDi | Princeton | NJ | Clinical Software |
| DePuy Synthes | West Chester | PA | Implants, Biomaterials |
| Devon Medical Products | King of Prussia | PA | Compression Therapy, Health Monitors, Stress Management Devices |
| DiamiR | Monmouth Junction | NJ | Brain Diagnostics |
| Diverse Biotech | Doylestown | PA | Cannabidiol Based Drugs |
| DoseCue | Philadelphia | PA | Dose Reminder Technology |
| Dr. Reddy's Laboratories | Princeton | NJ | Small Molecules, Custom Pharma Services |
| DSG | Malvern | PA | Clinical Trial Software |
| DSI InPharmatics | Harleysville | PA | CMC & Regulatory Consultants |
| Duchesnay USA | Rosemont | PA | OB/GYN Products |
| DWK Life Sciences | Millville | NJ | Lab Equipment |
| DZS Clinical Services | Monmouth Junction | NJ | Clinical Research, Software |
| EAG Laboratories | East Windsor | NJ | Analytical & Synthesis Services |
| ECS Metrology | Downingtown | PA | Metrology |
| Eisai | Exton | PA | Small Molecules |
| Eleison Pharmaceuticals | Princeton | NJ | Orphan cancer treatments |
| Ellodi Pharmaceuticals | Lawrence Township | NJ | Specialty Pharma |
| Elucida Oncology | Monmouth Junction | NJ | Nanoparticle Technology - Cancer Applications |
| Emergent BioSolutions | Princeton | NJ | Biologics, Contract Manufacturing, Biodefense |
| Emergent Biosolutions | Berwyn | PA | Biologics, Contract Manufacturing, Biodefense |
| Enalare Therapeutics | Princeton | NJ | Respiratory Therapies |
| Endo Pharmaceuticals | Malvern | PA | Small Molecules |
| Endo Pharmaceuticals | Malvern | PA | Small Molecules |
| Enterin | Philadelphia | PA | Targeting enteric nervous system of the gut |
| EpiVario | Philadelphia | PA | Small molecule inhibitor of ACSS2 |
| ERT | Philadelphia | PA | Clinical Services |
| Erytech Pharma | Princeton | NJ | Loading Red-Blood Cells with Therapeutics |
| Escalon Medical | Wayne | PA | Ophthalmology Devices |
| Ethos Biosciences | Philadelphia | PA | Assays & reagents |
| Evrys Bio | Doylestown | PA | Antivirals targeting non-viral human proteins |
| Exegenesis Bio | Lower Gwynedd | PA | Gene Therapy |
| ExpressCells | Philadelphia | PA | Custom Cell Lines |
| Flower Orthopedics | Horsham | PA | Surgical Plates, Screws, etc |
| FlowMetric | Doylestown | PA | Flow Cytometry Services |
| Focus Biomolecules | Plymouth Meeting | PA | Life Science Reagents |
| ForDoz Pharma | East Windsor | NJ | Development, manufacturing, and commercialization of value-added sterile complex injectable products |
| Fore Biotherapeutics | Philadelphia | PA | BRAF-Inhibitors, In-licensing others |
| Foresee Pharmaceuticals | Newark | DE | Drug Delivery tech |
| Freehold Surgical | New Hope | PA | Intracorporeal Retractors |
| Frontage | Princeton | NJ | Contract Research |
| Frontage | Exton | PA | Contract Research |
| Frontida BioPharm | Philadelphia | PA | Contract Manufacturing |
| Fujirebio Diagnostics | Malvern | PA | Biomarkers |
| Galera Therapeutics | Malvern | PA | Small molecules targeting oxygen metabolic pathways |
| Gene Universal | Newark | NJ | Gene Synthesis |
| Geneos Therapeutics | Plymouth Meeting | PA | Plasmid-based Neoantigen-targeted Cancer Therapies |
| Genesis Imaging Services | Princeton | NJ | Imaging Services |
| Genmab | Plainsboro | NJ | Biologics |
| GenPro Genome Profiling | Wayne | PA | Genetic variant discovery for drug targeting |
| GlaxoSmithKline | King of Prussia | PA | Small Molecules, Vaccines, Biologics |
| GlaxoSmithKline | Philadelphia | PA | Small Molecules, Vaccines, Biologics |
| Global Clinical Trials | Princeton | NJ | Clinical Research |
| Globus Medical | Audubon | PA | Minimally-invasive surgical tools |
| Group K Diagnostics | Philadelphia | PA | POC Diagnostics |
| Gyroscope Therapeutics | King of Prussia | PA | Gene Therapy |
| Harmony Biosciences | Plymouth Meeting | PA | Sleep & CNS disorders |
| HbO2 Therapeutics | Souderton | PA | Hemoglobin-based oxygen carrier |
| Healogix | Horsham | PA | Consulting |
| Helius Medical | Newtown | PA | Translingual neurostimulation device |
| Hexal | Princeton | NJ | Generics |
| Hologic | Newark | DE | Diagnostic, Imaging |
| Hovione | East Windsor | NJ | Contract Manufacturing |
| Hsiri Therapeutics | Media | PA | Therapies for Drug-resistant Bacteria |
| Hycult Biotech | Wayne | PA | Research Reagents |
| ICON plc. | Landsdale | PA | Clinical Trials, Consulting |
| ICON plc. | Yardley | PA | Clinical Trials, Consulting |
| Idera Pharmaceuticals | Exton | PA | Oligonucleotide therapies |
| iECURE | Philadelphia | PA | Gene Editing Therapies |
| ImCare Biotech | Doyelstown | PA | Drugs, Diagnostics |
| ImmproNano | Doylestown | PA | Immunological, proteomic and nanotechnology assays and services |
| Immunome | Exton | PA | Cancer Immunotherapy |
| Imvax | Philadelphia | PA | Personalized Vaccines, Immunotherapy |
| Incyte | Wilmington | DE | Small Molecules |
| Inference | Chesterbrook | PA | Clinical Trial Services |
| InfraScan | Philadelphia | PA | Handheld Brain Diagnostics |
| Innate Biologics | Phoenixville | PA | Naturally-Occurring, Engineered Bacterial Effector Proteins |
| Innocoll | Newtown Square | PA | Surgical / Tissue Implants |
| Innovative Supply Solutions | Southampton | PA | Clinical Trial Software |
| InnSight Technology | Wexford | PA | Ophthalmic Devices |
| Inovio Pharmaceuticals | Plymouth Meeting | PA | DNA Vaccines |
| Integra LifeSciences | Princeton | NJ | Medical Devices |
| Integral Molecular | Philadelphia | PA | Antibody Drug Discovery |
| Interius BioTherapeutics | Philadelphia | PA | Novel methods for in vivo cell-specific gene delivery |
| Intrance Medical Systems | Philadelphia | PA | Small Molecules |
| Invivotek | Trenton | NJ | Invivotek is a pre-clinical CRO with expertise in in vivo pharmacology and phenotypic characterization of genetically modified rodents to support drug discovery & development programs · AAALAC accredited 23,600 sq ft barrier facility · Disease models for oncology, immunology, metabolic diseases and microbiome |
| IO Biosciences | Doylestown | PA | Gene-Modified Cell Therapy |
| ITF Pharma | Berwyn | PA | Specialty Pharmaceuticals |
| IVIEW Therapeutics | Doyelstown | PA | Small molecule for ophthalmology |
| Jackson ImmunoResearch Laboratories | West Grove | PA | Secondary Research Antibodies |
| Janssen Pharmaceuticals | Titusville | NJ | Small Molecules, Biologics |
| Janssen Pharmaceuticals | Ambler | PA | Small Molecules, Biologics |
| Janssen Pharmaceuticals | Malvern | PA | Small Molecules, Biologics |
| Janssen Pharmaceuticals | Horsham | PA | Small Molecules, Biologics |
| Jazz Pharmaceuticals | Philadelphia | PA | Small Molecules |
| JBS Science | Doylestown | PA | Molecular Diagnostics for cancer |
| Jemincare Therapeutics | Princeton | NJ | Small Molecules |
| Johnson and Johnson | Skillman | NJ | Consumer Products |
| Johnson and Johnson | Skillman | NJ | Consumer Products |
| JRF GLOBAL | Audubon | PA | Non clinical GLP research services |
| Jubilant Radiopharmacies | Yardley | PA | Radiopharmaceuticals |
| Kantar Health | Horsham | PA | Pharmaceutical Consulting |
| KayoThera | Princeton | NJ | Small Molecule Immunotherapy for Solid Cancers |
| KBP BioSciences | Princeton | NJ | Small Molecules |
| Kendall Life Sciences | Bryn Mawr | PA | KLS is a unique, specialized consulting company that offers compliance and regulatory solutions |
| Keystone Clinical Studies | Norristown | PA | Clinical Studies |
| KVK Tech | Newtown | PA | Generics |
| Lannett | Philadelphia | PA | Generic Small Molecules |
| Larimar Therapeutics | Bala Cynwyd | PA | Small Molecules |
| Lavipharm | East Windsor | NJ | Small molecules |
| Life Diagnostics | West Chester | PA | ELISA, Antibodies |
| LifeLens Technologies | Warminster | PA | Physiologic Monitoring |
| LifeSensors | Malvern | PA | Protein Assays |
| LifeSign | Skillman | NJ | POC Diagnostics |
| LifeSplice Pharma | Malvern | PA | Splice modulating oligomers |
| LignaMed | Philadelphia | PA | Small Molecule |
| LipoSeuticals | Monmoth Junction | NJ | Sterile Injectables |
| Liquid Biotech | Philadelphia | PA | Cancer Diagnostics |
| Longevity Biotech | Philadelphia | PA | Synthetic Peptides |
| LucasPye Bio | Philadelphia | PA | Biologics CDMO |
| Lungpacer Medical | Exton | PA | Diaphragm Pacing Therapy |
| Lyophilization Technology | Warminster (Ivyland) | PA | Contract Lyophilization |
| Macroceutics | Monmouth Junction | NJ | DNA-Encoded Libraries, Drug Candidate Screening |
| Madrigal Pharmaceuticals | West Conshohocken | PA | Small Molecules |
| MakroCare | Princeton | NJ | Drug Development Partner |
| Marinus Pharmaceuticals | Radnor | PA | Specialty Pharmaceuticals |
| Masy BioServices | Hatfield | PA | Validation |
| Maxona Pharmaceuticals | King of Prussia | PA | Pain Therapies |
| Mebias Discovery | Philadelphia | PA | GPCR Drugs |
| Meda Biotech | West Berlin | NJ | Improved Nanotech Delivery |
| MedChemExpress | Monmouth Junction | NJ | Compound Library, Lab Reagents, Services |
| Medical Components | Harleysville | PA | Vascular Access Devices |
| Medical Device Success | Philadelphia | PA | Medical Device Consulting |
| Medicure | Princeton | NJ | Small Molecule |
| Melior Discovery | Exton | PA | High Throughput Screening for New Indications |
| Melior Pharmaceuticals | Exton | PA | Small Molecules |
| Menssana Research | Newark | NJ | Breath-based diagnostics |
| Merck | Lansdale | PA | Small Molecules, Vaccines, Biologics |
| Merck | North Wales | PA | Small Molecules, Vaccines, Biologics |
| Mineralys Therapeutics | Radnor | PA | Small Molecules |
| Mitochon Pharmaceuticals | Blue Bell | PA | Mitochondrial modulators |
| Moberg ICU Solutions | Ambler | PA | Medical Monitor, Other Devices |
| MOBILion Systems | Chadds Ford | PA | Analytical Diagnostic Technology |
| Nanocan Therapeutics | Princeton | NJ | Nanoparticle Drones |
| NanoCell Therapeutics | Berwyn | PA | Gene Therapy |
| Navinta | Ewing | NJ | Generics |
| Navitas Life Sciences | Princeton | NJ | Clinical Research |
| Navrogen | Philadelphia | PA | Humoral Immuno-Oncology |
| NephroDi Therapeutics | Philadelphia | PA | Small molecule for concentration disorders of the kidney |
| Neuland Laboratories | Princeton | NJ | API Manufacturer |
| NeuMeDx | Bristol | PA | Signal Morphology-based Impedance Cardiography products |
| Neuraptive Therapeutics | Philadelphia | PA | Therapies for nerve repairs |
| NeuroDx Development | Yardley | PA | Shunt Detection Device |
| Neuronetics | Malvern | PA | Medical Devices; TMS Therapy |
| Neuropathix | Doylestown | PA | Cannabinoids |
| NeuroRx | Radnor | PA | Small Molecules |
| NeuroRx | Wilmington | DE | Small Molecules |
| NewEast Biosciences | King of Prussia | PA | ELISA, Antibodies |
| NexEos Bio | Pottstown | PA | Diagnosis of eosinophil-related inflammatory diseases |
| Nexomics Biosciences | Rocky Hill | NJ | Protein & structural biology services |
| NexusPharma | Philadelphia | PA | NexusPharma - Oncology CRO with extensively characterized PDX models in over 15 cancer indications, database of compounds and their activities in various patient derived xenograft PDX tumor models or patient derived tumor cell lines. |
| Nflection Therapeutics | Wayne | PA | Development of therapies for Neurofibromatosis 1 |
| Nia Therapeutics | Radnor | PA | Neural interfaces for memory restoration |
| NiKang Therapeutics | Wilmington | DE | Small Molecules for Oncology |
| Noramco | Wilmington | DE | Opiate-derived APIs & Reference Standards |
| Notitia Biotechnologies | Monmouth Junction | NJ | Microbiome |
| Novaflux | Princeton | NJ | Device cleaning technology |
| Novapeutics | Philadelphia | PA | Small molecule for cellular regeneration |
| NovaRock Biotherapeutics | Ewing | NJ | Antibody Therapeutics |
| Novasep | Boothwyn | PA | Purification Systems |
| Novitium Pharma | East Windsor | NJ | Generics |
| NovoPedics | Princeton | NJ | Implantable meniscus repair |
| Nth Analytics | Princeton | NJ | Clinical Software Services |
| Nuventra Pharma Sciences | Exton | PA | Nonclinical & Clinical Pharmacology Consulting. PK, PD, Population PK, TK, Regulatory, Writing, Clinical Operations. |
| Oblato | Princeton | NJ | Small Molecules |
| OCMS Bio | Wynnewood | PA | Hybridoma Screening |
| Ocugen | Malvern | PA | Sight-threatening Diseases |
| OcuMedic | Mullica Hill | NJ | Contact Lens for Drug Delivery |
| Oncoceutics | Philadelphia | PA | Imipridones |
| Onconova Therapeutics | Newtown | PA | Tumor-Targeting Small Molecules |
| OncoSec Medical | Pennington | NJ | Electroporation Drug-Delivery |
| Opsidio | Bryn Mawr | PA | Monoclonal Antibody |
| Optimeos Life Sciences | Princeton | NJ | Encapsulation Technology |
| OptiNose | Yardley | PA | Drug delivery platform |
| Optys Tech | Philadelphia | PA | Mass Spec Data Analysis |
| Opus Genetics | Philadelphia | PA | Ophthalmology Gene Therapy |
| Orchestra BioMed | New Hope | PA | Medical devices |
| Ori Biotech | Philadelphia | PA | Cell & Gene Therapy Manufacturing |
| Origin | Princeton | NJ | Nitric Oxide-emitting Devices |
| Orsenix | Wilmington | DE | Novel oral form of arsenic trioxide |
| Orthobond | Princeton | NJ | Medical Implant Surface Chemistry |
| OrthogenRx | Doylestown | PA | Treatments for musculoskeletal conditions |
| Outlook Therapeutics | Monmouth Junction | NJ | Biosimilars |
| Oyster Point Pharmaceuticals | Princeton | NJ | Ophthalmology Indications |
| Palladio Biosciences | Horsham | PA | Small Molecules |
| Palvella Therapeutics | Wayne | PA | Small Molecules |
| Panavance Therapeutics | Berwyn | PA | Small Molecules for Cancer |
| Panorama Medicine | Bala Cynwyd | PA | Drug discovery platform for interventions for RNA defects in disease |
| Papyrus Therapeutics | West Chester | PA | Biologics for Oncology |
| Paratek Pharmaceuticals | King of Prussia | PA | Small Molecules |
| Passage Bio | Philadelphia | PA | Gene Therapy |
| Patwell Pharmaceuticals | Coatesville | PA | Pharmaceutical packaging & labeling |
| PCI Pharma Services | Philadelphia | PA | Contract Manufacturing, Services |
| Peroxitech | Philadelphia | PA | Treatment for acute lung injury |
| Pennsylvania Biotechnology Center | Doylestown | PA | Nonprofit life sciences incubator |
| PhaseBio Pharmaceuticals | Malvern | PA | Prolonged Half-Life, Purification Improvements |
| Photocure | Princeton | NJ | Diagnostics & Small Molecules |
| PhotoSonix Medical | Fort Washington | PA | Biofilm infection treatment |
| Pinpoint Therapeutics | Philadelphia | PA | Autophagy inhibitors to treat cancer |
| Polyaurum | Philadelphia | PA | Biodegradable gold nanoparticles for diagnostic and therapeutic indications |
| PolyCore Therapeutics | Philadelphia | PA | Small Molecules |
| PortaScience | Moorestown | NJ | Diagnostics |
| PRA Health Sciences | Blue Bell | PA | Clinical Research |
| Praxgen Pharmaceuticals | Princeton | NJ | Generics |
| PreCOG | Philadelphia | PA | Clinical Research |
| Prelude Therapeutics | Wilmington | DE | Cancer Treatments |
| ProBioPharm | Doylestown | PA | Strategy & Business Development Consulting |
| Progenra | Malvern | PA | Therapies derived from ubiquitin proteasome pathway |
| Projections Research | Phoenixville | PA | Consulting |
| ProPhase Labs | Doylestown | PA | Generic OTC |
| Provid Pharma | Monmouth Junction | NJ | Contract Research |
| PSG Life Sciences | Princeton | NJ | Management consulting firm advising companies on issues of sales, marketing and business development strategy, operations and tactical execution |
| Pulse Biomedical | King of Prussia | PA | Computer-based Cardiology Equipment |
| Puresyn | Malvern | PA | Plasmid and Adenovirus Purification |
| QPS | Newark | DE | QPS is focused on discovery, preclinical & clinical drug development with research sites worldwide |
| Quartesian | Princeton | NJ | Clinical Research Services |
| Quotient Sciences | Garnet Valley | PA | Quotient Sciences is a global pharmaceutical development organization, providing formulation development, clinical pharmacology, and clinical & commercial manufacturing |
| Quotient Sciences | Boothwyn | PA | Quotient Sciences is a global pharmaceutical development organization, providing formulation development, clinical pharmacology, and clinical & commercial manufacturing |
| RapidTrials | Wynnewood | PA | Clinical Trial Management |
| Reaction Biology | Malvern | PA | Assay Services & Protein Production |
| ReGenTree | Princeton | NJ | Therapeutic Peptides |
| Reliefband Technologies | Horsham | PA | Anti-nausea wristband |
| Renovacor | Wynnewood | PA | Recombinant adeno-associated virus-based gene therapy |
| Rex Medical | Conshohocken | PA | Medical Devices |
| Rhythmedix | Mt. Laurel | NJ | Wearable Cardiac Monitor |
| Rithem Life Sciences | Wilmington | DE | Portable Lifesaving Products |
| Rockland Immunochemicals | Limerick | PA | Antibodies & Assays |
| R-Pharm US | Princeton | NJ | Acquiring Small Products |
| SanaVita Medical | Telford | PA | Contract manufacturing & device processing services for implantable biomaterials, controlled drug release, and combination products |
| Sandoz | Princeton | NJ | Generics, Biosimilars |
| SciAn Services | Philadelphia | PA | Clinical Trials |
| Sciecure Pharma | Monmouth Junction | NJ | Generics |
| Score Pharma | Exton | PA | |
| SDIX | Newark | DE | Diagnostics |
| Sedor Pharmaceuticals | Paoli | PA | Acquisition & Development of Drug products |
| Sekisui Diagnostics | Exton | PA | Diagnostics |
| Seneca Therapeutics | Blue Bell | PA | Oncolytic immunotherapeutic |
| Septodont | Lancaster | PA | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| SFA Therapeutics | Jenkintown | PA | Microbiome-derived metabolites as drugs |
| Sharp | Conshohocken | PA | Contract clinical trial services and commercial packaging services |
| Shenandoah Biotechnology | Warwick | PA | Proteins, antibodies, etc. |
| Shifa Biomedical | Malvern | PA | Structure-based drug discovery |
| Shinkei Therapeutics | Princeton | NJ | CNS products |
| Siegfried | Pennsville | NJ | Contract Drug Manufacturing, APIS, Development |
| Siemens Healthineers | Malvern | PA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Sigmapharm Laboratories | Bensalem | PA | Formulation of generics |
| Signant Health | Plymouth Meeting | PA | eClinical Solutions |
| Simphotek | Newark | NJ | Light Therapy |
| Skyran Biologics | Philadelphia | PA | Ophthalmological Small Molecule |
| Slayback Pharma | Princeton | NJ | Generics |
| Smooth Drug Development | Wilmington | DE | Clinical Research |
| Solentim | Wayne | PA | Automated Single-Cell Cloning, Cell Line Engineering |
| Soligenix | Princeton | NJ | Lipoprotein Delivery, Small Molecules |
| Sonnest | Philadelphia | PA | Electrically sensitive imaging agent for cardiac ultrasound |
| Sonnet BioTherapeutics | Princeton | NJ | Cytokine-derived therapeutic candidates |
| Soterius | Lawrenceville | NJ | Outsourced clinical safety, pharmacovigilance, medical affairs, and technology-enabled services |
| Soterius | Princeton | NJ | Outsourced clinical safety, pharmacovigilance, medical affairs, and technology-enabled services |
| SP Lab Services | Southampton | PA | Contract Services |
| Spark Therapeutics | Philadelphia | PA | Singe Dose Gene Therapy |
| Spirovant Sciences | Philadelphia | PA | Gene Therapy - Lung Diseases |
| SteroTherapeutics | Doylestown | PA | NASH treatments |
| STI Pharma | Newtown | PA | Acquisition, Development & Marketing of Specialty Pharmaceuticals |
| Strados Labs | Philadelphia | PA | Respiratory Management Device |
| STRATA Skin Sciences | Horsham | PA | UV Therapy |
| Suvoda | Conshohocken | PA | Clinical Trial Software |
| SwanBio Therapeutics | Bala Cynwyd | PA | Gene Therapy |
| Syncro Medical | Langhorne | PA | Software development |
| Syneos Health | Princeton | NJ | Clinical Development |
| Syneos Health | Blue Bell | PA | Clinical Development |
| Syneos Health | Newtown | PA | Clinical Development |
| Synergy Biomedical | Wayne | PA | Biomaterials, Grafts |
| Taiho Oncology | Princeton | NJ | Oncology small molecules |
| TalexMedical | Malvern | PA | Ear Moulding System |
| Tamuro Bio | Wayne | PA | NASH Treatment |
| Tavanta Therapeutics | Radnor | PA | Specialty Pharma |
| Tavotek Biotherapeutics | Lower Gwynedd | PA | Biologics |
| TAXIS Pharmaceuticals | Monmouth Junction | NJ | Antibiotics |
| TE Connectivity | Berwyn | PA | Medical Devices |
| TELA Bio | Malvern | PA | Bioscaffolds, meshed |
| Teleflex Medical | Wayne | PA | Surgical and Medical Devices |
| Teligent | Buena | NJ | Contract Development & Manufacturing |
| Terran Biosciences | Wilmington | DE | Medical imaging device; small molecule for neurological disorder |
| Teva | West Chester | PA | Small Molecules |
| The Clinical Trial Center | Jenkintown | PA | Clinical Research Facility |
| Theradex | Princeton | NJ | Oncology Clinical Research |
| Thrombolex | New Britain | PA | Endovascular catheters |
| Tmunity Therapeutics | Philadelphia | PA | Cancer Immunotherapies |
| Trace Orthopedics | Philadelphia | PA | Minimally-invasive Tendon Surgery |
| TradeCraft Clinical Research | Wayne | PA | Clinical Research |
| Treovir | Philadelphia | PA | Oncolytic HSV immunotherapy |
| Trevena | Chesterbrook | PA | GPCR-targeted Drug Discovery |
| Trice Medical | Malvern | PA | Illumination device, handheld joint imaging |
| Tris Pharma | Monmouth Junction | NJ | Drug Delivery Technologies |
| Tunnell Consulting | King of Prussia | PA | Consulting |
| TX3 Services | Blue Bell | PA | IT Consulting for Life Sciences |
| UBC | Blue Bell | PA | Biopharmaceutical Consulting & Services |
| Ufovax | Wilmington | DE | Vaccine Platform Technology |
| Uncommon Innovation | Devon | PA | Medical Device Design & Regulatory Consulting |
| Union Surgical | Doylestown | PA | Fracture Pin |
| Vallon Pharmaceuticals | Philadelphia | PA | CNS Treatments |
| Valo Health | Princeton | NJ | Drug Discovery & Development Engine |
| VascuLogic | Princeton | NJ | Image-guided Medical Devices and Diagnostic Products |
| Veeva Systems | Fort Washington | PA | Life Science Software |
| Veeva Systems | Radnor | PA | Life Science Software |
| Venatorx Pharmaceuticals | Malvern | PA | Antibacterials |
| Vensun Pharmaceuticals | Yardley | PA | Generics |
| Verismo Therapeutics | Philadelphia | PA | Cell Therapy |
| Verity Pharmaceuticals | Wayne | PA | Specialty genitourinary therapies |
| Verrica Pharmaceuticals | West Chester | PA | Topical therapies |
| Vesper Medical | Wayne | PA | Venous Stent |
| Vibe Pharmaceuticals | Philadelphia | PA | Specialized Autologous Bone Cells as Osteoporosis Treatments |
| Vironika | Wynnewood | PA | Tumor virus targeting |
| Virpax Pharmaceuticals | West Chester | PA | Drug Delivery System for Pain |
| VIRTUS PHARMACEUTICALS | Langhorne | PA | Specialty niche pharmaceuticals |
| Vitara Biomedical | Philadelphia | PA | Artificial Womb Technology |
| ViTToria Biotherapeutics | Philadelphia | PA | T Cell Therapies |
| Vivozon | West Windsor | NJ | Pain Therapy |
| Vynamic | Philadelphia | PA | Healthcare, Life Science Management Consulting |
| Vyome Therapeutics | Princeton | NJ | Multifactorial treatment of antibiotic-resistant acne |
| WCCT Global | Langhorne | PA | Clinical Research |
| WCG Clinical | Princeton | NJ | Clinical Trial Services |
| West Pharma | Exton | PA | Pharmaceutical Supplier |
| WindMIL Therapeutics | Philadelphia | PA | Cell-based Immuno-Oncology |
| Windtree Therapeutics | Warrington | PA | Peptides |
| Worldwide Clinical Trials | King of Prussia | PA | Clinical Research |
| WuXi Apptec | Philadelphia | PA | Contract Biologics, Medical Devices |
| XEME Biopharma | Monmouth Junction | NJ | Autologous Biologic Therapy |
| Xybion | Princeton | NJ | Cloud LIMS, Quality |
| XyloCor Therapeutics | Philadelphia | PA | Gene Therapy |
| Xyntek | Newtown | PA | Pharma, Device, Healthcare IT Consulting |
| Zynerba Pharmaceuticals | Devon | PA | Transdermal synthetic cannabinoid treatments |
| Aptatek BioSciences | Princeton | NJ | Small Molecule Biomarker Sensor |
| ArrePath | Princeton | NJ | Machine learning-based platform for the discovery of new classes of anti-infectives |
| Orcosa | Ewing | NJ | Orally Disintegrating Tablet |
| Proteovant | King of Prussia | PA | Small Molecule Protein Degraders |
| EDDA Technology | Princeton | NJ | Computer-assisted Radiology |
| Cellport Software | Exton | PA | Software for Cell Culture & Manufacturing |
| Magic Hat Consulting | Fort Washington | PA | Boutique consulting firm partners with life science companies to optimize operations |
| ONOCOR | West Chester | PA | atheter-based retrieval system |