companies

The Big4Bio Company to Watch Program
April 2024: Elegen

    THE COMPANY/THE MISSION Removing Bottlenecks in Synthetic Biology With Cell-Free Synthesis of Long and Complex DNA Elegen’s mission to unlock the promise of synthetic biology by eliminating a critical bottleneck in the supply of synthetic DNA     THE TECHNOLOGY, PART 1 Podcast: Solving Major Bottlenecks in Genetic Medicine and SynBio With DNA […]

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Unlocking the Power of RNA, Part 2

In the second feature on CircNova, CSO Joe DeAngelo explains the science behind the company and why he thinks their technology can unlock the power of RNA to drug targets that have previously been undruggable. Companies to Watch – CircNova by Marie Daghlian CircNova believes circular RNA has great potential benefit for therapeutic development by […]

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The Big4Bio Company to Watch Program
September 2023: CircNova

THE COMPANY/THE MISSION   Unlocking the Power of RNA, Part 1 CircNova aims to leverage AI to generate, analyze, and identify non-coding circular RNA for therapeutic development       Unlocking the Power of RNA, Part 2 CSO Joe DeAngelo explains the science behind the company and why he thinks their technology can unlock the […]

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Unlocking the Power of RNA, Part 1

In the first of two features on CircNova, CEO Crystal Brown and CSO Joe DeAngelo recount the spark behind the formation of the company and its mission to enable the development of therapeutics for major unmet clinical needs. The second feature will discuss thinking behind CircNova’s technology. Companies to Watch – CircNova by Marie Daghlian […]

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The Big4Bio Company to Watch Program
June 2023: Startup Stadium Finalists at BIO 2023

Start-Up Stadium is designed to provide start-up companies with the opportunity to engage key members of the investment community, venture philanthropy groups, strategic partners, and non-dilutive capital at the world’s largest biotechnology partnering event. During the 2023 BIO International Convention select finalists from around the world will share a quick pitch showcasing new technologies and therapeutic solutions […]

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Podcast: Pioneering Fully Programmable Medicines

In the third of four features on Senda Biosciences, we spoke to Senda CEO Guillaume Pfefer and Senda Chief Platform Officer Stuart Milstein, about its platform technology, how it is building an atlas of natural nanoparticles, and how its work is leading to a pipeline of programmable medicines. Companies to Watch – Senda Biosciences The Big4Bio […]

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Medicines with Unlimited Possibility

The second of four features on Senda Biosciences, based on Big4Bio’s interview with CEO Guillaume Pfefer and Chief Platform Officer Stuart Milstein, focuses on the company’s technology platform – designed to harness nature’s codes to program molecules within and to the cell – and its potential to treat a broad range of diseases. Companies to […]

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The Big4Bio Company to Watch Program
April 2023: Senda Biosciences

  THE COMPANY/THE MISSION Programming Medicine to Send the Right Information to the Right Cell Senda Biosciences is on a mission to harness powerful molecular interactions that have evolved over millennia between humans, plants, and bacteria to develop new types of medicines.   THE TECHNOLOGY, PART 1 Medicines with Unlimited Possibility Discussing the company’s technology […]

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Programming Medicine to Send the Right Information to the Right Cell

In the first of four features on Senda Biosciences, Big4Bio spoke with CEO Guillaume Pfefer and Chief Platform Officer Stuart Milstein about how and why the company was founded, and how molecular connections among different kingdoms of life that have co-evolved over millennia may hold the key to addressing the challenges of delivering nucleic acid […]

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The Big4Bio Company to Watch Program
September 2022: Life Science Cares

Life Science Cares leverages the power of the life science industry to solve one of our most intractable social issues—poverty. They currently operate in locations that boast a critical mass of companies working in biotech, pharmaceuticals, medical technology, and research: Boston, Philadelphia, San Diego and the San Francisco Bay Area — the Big4Bio regions. Life […]

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