This webinar will highlight common preclinical safety flags to consider in order to assist mitigating clinical trial risk, including recommendations from both FDA and EMA guidance documents. Our scientists will also discuss a tiered approach to clinical validations and tools to accelerate translation of preclinical data to the clinic through a brief overview of human PK profile projections, human equivalent dose predictions, and PK/PD modeling techniques.

Presenters

• Colin Pattison, BSc, Functional Manager, Charles River
• Jason W. Boggs, BSc, Senior Research Scientist, Charles River
• Lauren Black, PhD, Senior Scientific Advisor, Charles River