Even the best ideas in the life sciences are painfully difficult to turn into reality, especially if they are radically new or different. Older generations—of people and products—do not yield easily. How do scientists and entrepreneurs push past the status quo while respecting collective experience and wisdom? At our upcoming Xchange forum in San Francisco, company founders and visionary scientists will share how they are pursuing new ideas and breaking biotech boundaries. They’ll offer fresh takes on cutting-edge medical science; new experiences and perspectives from unlikely executives; and new technology to fight seemingly intractable problems.